Unlocking the secret of a good night’s sleep is key to re-invigorating body and mind. The body’s release and use of melatonin is vital to a restful, restorative sleep and Melatonin ZnSe is the sleep disorder treatment that releases melatonin at just the right time. Nighttime is the most vital time for Melatonin production as it regulates our sleep cycle. As such, this melatonin supplement is the ideal melatonin for sleep and can counter the debilitating effects of insomnia.
Watch the video above to hear world melatonin expert Dr. Pierpaoli’s who developed Melatonin Zn Se interviewed about his creation
Busy lives, our environment, the foods we consume and factors like our age all affect our ability to get a good night’s sleep.
Melatonin ZnSe, a proven sleep disorder treatment, helps the body’s supply of melatonin be maintained at more ‘youthful levels’ - as our body produces less melatonin as we age. Ensuring that melatonin for sleep is delivered at the optimum time, Melatonin ZnSe is a melatonin supplement with added Zinc and Selenium, which have other restorative qualities.
Melatonin benefits our body by regulating our awake and asleep times, which in turn lets our body find time to repair damaged cells and allows us to switch off mentally. Importantly, it helps the body get rid of harmful free-radicals and repair damaged cells.
By adding Zinc and Selenium with the Melatonin supplement, the restoration of body and mind is rendered even more effective. Selenium is one trace element that is a powerful force against oxidative damage. Zinc is equally important as one of the most important trace enzymes in the body. When the body is nicely at rest, these vital trace elements can best repair cells.
Melatonin is produced by the Pineal Gland, a pea sized structure located in the centre of our brains. Vital for bodily rhythms and especially the rhythms that regulate our awake and sleep cycle, this is the control centre for differentiating night and day. It’s also central in protecting our hormonal system, working to regulate immunity, repair our body’s cells, relax muscles and rest our minds ready for the following day. Not only do we feel better following Melatonin’s nighttime release, our body’s immune system is repaired.
Ideally, melatonin should be released at nighttime – when our body naturally requires melatonin. An extensive study found that melatonin benefits are most pronounced from 1am to 3 am, with nightly release from the pineal gland. Melatonin ZeSe does exactly this – at the right moment during the night sleep cycle. This is something you won’t find with other melatonin supplements that have been designed to release constantly. These constant release supplements carry the danger of reaching a plateau that maintains an artificial level for hours, mimicking the night peak. This puts our body’s repair cycle out of sync and therefore diminishes the effectiveness.
Another form; Sublingual (dissolved under the tongue) melatonin, could also disrupt sleep by giving an early peak - ceasing to be effective and again being detrimental to the body’s natural patterns.

This graph highlights that Professor Pierpaoli’s Melatonin Zn Se formula mimics the night peak of melatonin. Note that sublingual melatonin tested peaks too soon and that time released formulas peak too late.
Sleep disorders can become even more prevalent as we get older; that’s why on a simple level, you’ll notice that young people and teenagers can sleep for longer periods than older people. One major reason is that it’s because teenage bodies produce more Melatonin than their older counterparts. Younger people are more robust when it comes to their immune system, which is linked to the amount of quality sleep and the time they have to repair the body’s cells. Other sleep aids like tryptophan, valerian and melatonin on its own don’t work to improve the level of melatonin naturally produced and even though melatonin side effects are quite minimal, melatonin safety is paramount. This is why dr pierpaoli has developed the treatment to prevent melatonin overdose, tackle the withdrawal symptoms that are associated with unnaturally high levels of melatonin and avoid any associated dangers.
Melatonin ZnSe tablets are developed by world expert Dr. Pierpaoli – the leading authority on melatonin. They are manufactured in Italy and only contain pharmaceutical grade melatonin.
Providing melatonin, zinc and selenium at the right time allows the body and mind to relax soundly at night. With Melatonin ZnSe you can be on top form the following day, as you awake feeling rested and thoroughly revitalised.
By taking Melatonin ZnSe just before bedtime, half to one (maximum two) 3mg tablets can enable a quality sleep - and all the benefits that this brings to the body and mind.
Side effects of Melatonin ZnSe are generally minimal and melatonin itself is used across a wide variety of conditions with success and there is no evidence of melatonin causing breast enlargement in females.
Providing melatonin, zinc and selenium at the right time allows the body and mind to relax soundly at night. With Melatonin ZnSe for sleep, you can be on top form the following day, as you awake feeling rested and thoroughly revitalised.
Melatonin should not be used by women who are pregnant or nursing (since no one knows how excessive exposure to the hormone might affect a foetus or infant); people with severe allergies or autoimmune diseases (Melatonin could exacerbate such conditions by stimulating the immune system); people with immune-system cancers such as lymphoma or leukaemia (for the same reason), and healthy children (who already produce it in abundance). Women trying to conceive should also think twice about taking the hormone, since high doses can act as a contraceptive.
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Disclaimer: Please note that only your own physician can determine your precise needs, but in order to give you some information these answers are based upon the ‘average person’ and clinical/ published results.
I recently purchased PraevoSkin® cream and would like to know the amount of melatonin that is delivered in say, one-quarter teaspoon of cream or whatever concentration ratio you have that enables me to tell how much I'm getting?
Unfortunately, the manufacturer of PraevoSkin cream is currently keeping the precise amount of melatonin in the cream a proprietary secret; we expect that they are doing so until their patents are active. You can rest assured that the product you are using is exactly the same as that used in the German trials.
Does Praevo Skin Cream have fragrance in it?
Yes a fragrance is added to the Praevo Skin cream, although it is extremely mild and smells a little like vitamin E.
I have been using Dr Pierpaoli's melatonin for 6 weeks and the results are hard to believe. It appears to have kick started my thyroid gland as my tests are back to normal and I have not had any thyroid medication for 2 and a half months. Almost every symptom has disappeared.
I gave some of my tablets to my husband who is also pretty excited about this as he claims that he does not have to get up to the bathroom during the night.
Other features we've experienced is better and deeper sleep, more energy and awaking feeling well rested. This in turn has allowed us to exercise for 45 minutes with ease. Incidentally,we are 66 and 61 years old
JR., New Zealand
I had to write to say how impressed I am with this supplement. It works! This is a most excellent formulation of Melatonin and I am now looking forward to receiving my next order. I am really grateful to have this kind of help during my difficult menopausal years.
S.L., Canada
I found that the difference with Melatonin Zn Se ® is very substantial. Normally I have to take at least 9mg of other Melatonin's to aid my sleep, but I found that 3mg of Melatonin Zn Se ® was much more effective. So much so, that I am now only using half a tablet!
Phil Micans PharmB
Melatonin Zn Se ® represents a breakthrough in the use of Melatonin supplements; call it genius or luck, but my patients are now obtaining excellent results with it!
Walter Pierpaoli, MD
Melatonin Zn Se ® is without doubt the most effective Melatonin I've ever used. Normally I haven't noticed any strong sleep enhancement effects with other types, but Melatonin Zn Se ® almost knocks me out!
David Butler BSc