Treating gout effectively can be easily achieved with a Colchicine dosage. Avoiding the need to take potentially reactive anti-inflammatory drugs, plant extract Colchicine inhibits the delivery of white blood cells into the areas of the body affected by gout. This means swelling, and the associated pains from the condition are considerably reduced.
Colchicine is designed to treat acute gout and to be used as a preventative. When gout strikes the symptoms are similar to recurrent occurrences of inflammatory arthritis – pain at the site of flexible joints. In the case of gout, a build-up of uric acid forms crystals in the joints and causes the body to react.
Traditionally, a natural extract from the plant commonly known as the autumn crocus, meadow saffron or colchicum autumnale, Colchicine has been used to treat swelling and inflammation for literally thousands of years. In tablet form, it’s fully approved for purpose and is as effective as existing NSAIDs (Non-steroidal anti-inflammatory drugs) for gout, but derived from entirely natural sources.
The facts about gout
Traditionally known as “rich man’s disease”, or the “disease of kings”, gout is actually increasing in frequency and is estimated to affect 1 – 2% of people in the Western world at some point in their lives. It’s also much more likely to occur as we get older and far more prevalent in men than women.
Caused by a build-up of uric acid and the subsequent accumulation of crystals in joints, gout’s main catalyst is hyperuricemia – too much uric acid in the system. At the root of this condition, a number of factors affect whether we develop gout.
Key reasons why hyperuricemia happens in the first instance can be down to a range of factors - from diet to genetics. Being overweight is widely believed to be a cause –especially in men. By extension, an over-consumption of alcohol, imbibing too many sweetened drinks and even eating too much meat are all thought to play a part. Genetically, one can be born with a propensity to retain urate and not excrete it efficiently enough. Physical trauma and surgery are less common, but valid causes for the onset of hyperuricemia.
How is the body affected by gout?
Although there are a number of areas of the body that can be affected by gout, in half of cases, the big toe is the prime site of manifestation. Specifically, the metatarsal-phalangeal joint becomes swollen and sensitive, but it can affect any flexible joint in the body and even the kidneys.
Essentially, a sporadic elevation in the level of uric acid in the blood means that crystals can form, and these can accumulate in joints and tendons. We naturally excrete this waste product – filtered through the kidneys. Not getting rid of enough uric acid, or producing too much in the first instance (both known as Hyperuricemia) are usually the main causes.
When the body’s uric acid accumulates, crystals build up meaning that tissue becomes irritated. The joints then swell and become painful. This is because white blood cells rush to the defence of the body at the site of the deposits, and a lactic acid build up ensues. The body’s natural protective mechanism is activated, and inflammatory enzymes are produced, hence swelling and discomfort occurring.
If the excess gathering of uric acid is not tackled properly, then the crystals that are formed can clump together to trigger permanent and progressive damage (and pain) to joints and bone. These are known as “tophi” – and are painful, unsightly nodules that can lead to bone deformities.
How Colchicine works
When a Colchicine dosage is taken, its mechanism of action is to reduce the number of white blood cells that rush to the site of inflammation in the body. This essentially breaks the cycle of inflammation and lactic acid build-up, therefore, swelling and pain can be reduced.
Colchicine has been used for treating gout-like symptoms since some of the earliest medical records began – on papyrus in Egyptian times. Since then, it’s proven a valuable weapon in the battle against gout. Although Colchicine can treat a variety of conditions associated with inflamed and swollen parts of the body, it can also treat familial Mediterranean fever, pericarditis, and Behçet's disease. Research into its potential application to treat cancer-infected cells is ongoing but encouraging.
Although Colchicine is originally derived from a plant extract that’s FDA approved, it’s always necessary to ask your doctor or pharmacist before using it. For example, there may be certain medications that are unsuitable to take alongside Colchicine or in rare cases, side effects such as nausea or an allergic reaction may occur. Of course, reading the label thoroughly is necessary before taking any course of medication.
Depending on the strength of the Colchicine, for sudden gout attacks a general rule is one tablet, two to four times a day, monitoring the symptoms and being patient to see the positive effects.
For a naturally-derived way to ease inflammation and diminish the pain associated with gout’s symptoms, step up to Colchicine.
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