Think clearly, think Nicergoline

Nicergoline is part of a family of drugs known as ‘smart drugs’ or nootropics, which are used to help improve impaired brain function. Nicergoline enhances mental clarity, perception and concentration.

Originally introduced for disorders affecting blood supply to the brain, it soon became apparent that Nicergoline had other considerable benefits.

It has now been found to enhance concentration and improve mental clarity, perception and vigilance. Nicergoline is also currently being used to treat forms of dementia, including Alzheimer’s disease.

What are the effects of Nicergoline?

Nicergoline has been around for more than 30 years, but its usage and benefits have emerged over time.

Studies into the effects of Nicergoline have revealed its potential for improving mental agility, and it’s now one of the most highly regarded brain concentration supplements on the market.

Nicergoline works by stimulating what’s known as alpha-adrenolytic action, this activates the brain’s metabolism. It is an ergot derivative and therefore has a chemical resemblance to codergocrine mesilate and is used for similar purposes.

The most well-known codergocrine mesilate is perhaps Hydergine, which boosts vigilance and perception, although the effects of Nicergoline are somewhat different. Whilst Hydergine stabilises oxygen and increases mental ability, (thereby extending a person’s useful mental workload), the principal effects of Nicergoline are to boost mental clarity, vigilance and perception.

How does Nicergoline work?

When Nicergoline was first introduced it was as a vasoactive drug, in other words a drug used to exert an effect on blood vessels. Over time however, it proved to have a more complex pharmacological profile than scientists had first realised.

Nicergoline works by activating the brain’s metabolism and increasing arterial flow, lowering vascular resistance and improving the use of glucose and oxygen. The effect of this is improved mental agility, clarity, perception and concentration.

Nicergoline is also known to act on the blood itself, inhibiting platelet aggregation and blood clots. Plate aggregation is when the colourless, irregularly-shaped platelets found in blood, clump together. This is part of the sequence of events that leads to blood clots.

What is Nicergoline useful for?

Nicergoline has been widely used in hospitals to regulate and improve brain disorders caused by metabolic-vascular insufficiencies. It’s mainly used to enhance mental clarity, perception and concentration.

Nicergoline is currently prescribed to treat senile dementia, by activating the brain’s metabolism and improving uptake of glucose and oxygen. Studies on animals have shown that Nicergoline can increase nerve growth in an older brain.

Nicergoline is also useful in treating a number of blood-related problems, such as transient ischemia (occasional blood supply difficulties) platelet hyper-aggregability (sticky blood platelets), improving limb blood-irrigation and lung blood-circulation.

Nicergoline has further benefits in the treatment of migraines stemming from vascular problems, and for macular degeneration, a common age-related eye problem.

Given its ability to act on blood vessels and blood itself, Nicergoline is useful for the following conditions:

  • Acute and chronic cerebral metabolic-vascular disorders, such as the hardening of the walls of the blood vessels in the brain, thrombosis (blood clot in a cerebral blood vessel), obstructions of a blood vessel in the brain and occasional blood supply problems to the brain.
  • Diseases of the arteries affecting the limbs, Raynaud’s Disease and other conditions caused by altered peripheral blood flow.
  • Problems of a vascular nature, such as dizziness, auditory hallucinations and hearing impairments caused by a deficiency in the conductive hearing organs.
  • Corio-retinal vascular disorders – damage to the retina of the eye caused by blood supply problems, macular degeneration and a hardening of the walls of the blood vessels in the retina.

Recommended Nicergoline dosages

Recommended Nicergoline dosages vary according to the condition being treated. For age-related macular degeneration and blood disorders, a dosage of 5mg once, twice or three times daily is usually sufficient. For the treatment of senile dementia, 30mg to 60mg may be recommended.

As with all nootropic drugs, occasional breaks from the treatment regime are advised. The side effects of Nicergoline are minimal and are usually an indication of incorrect dosage.

Nicergoline is a safe, effective brain concentration supplement, highly recommended for improved mental vigilance and clear thinking.


What our customers say...

We are very pleased that IAS is stocking Nicergoline now, here in Japan it is one of the most popular of the smart-drugs.
Y.K., Japan.


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What our customers say

We are very pleased that IAS is stocking Nicergoline now, here in Japan it is one of the most popular of the smart-drugs.
Y.K., Japan.

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