Pyritinol treatment can be beneficial to many of us as we age and our bodies slow down. When we realise our minds are simply not as sharp as they were and our physical abilities are lessened, then it could be time to look at supplements.
A pyritinol dosage is proven to have positive effects when it comes to improving memory, vigilance and concentration.
A vitamin B6 derivative, pyritinol belongs to a family of drugs known as nootropics. This is a class of drugs and supplements that can help our ageing brains.
A long established nootropic, pyritinol can enhance memory, cognition, attention and concentration. Physical and psychological exhaustion, altered sleeping and waking rhythms, and symptoms related to senility and pre-senility have all been shown to respond positively to pyritinol.
Perhaps the oldest of the nootropics still in use, pyritinol was commercially launched by Merck in 1961 and has been extensively researched and used throughout Europe. Its geographical concentration means pyritinol is not well known in the US, however – despite being available across Europe for half a century.
Common names for commercially available versions of this nootropic are pyritinol cerbon 6, pyrithioxine and pyridoxine disulfate.
Pyritinol treatment has been used for a range of brain disorders including cerebral arteriosclerosis, and has proven helpful when treating people with traumatic coma caused by head injuries. There’s evidence that pyritinol has excellent immune system enhancing capabilities and potent antioxidant properties, and may be especially beneficial for those suffering from rheumatoid arthritis.
The positive pyritinol effects are experienced because this is a superior antioxidant to other nootropics such as centrophenoxine. Many pyritinol reviews over the half century since its launch indicate pyritinol is particularly effective against hydroxyl - one of the most common free radicals continuously produced by human cells.
While the body produces enzymes to help it deal with superoxide and hydrogen peroxide, it has no enzymatic defences to protect against hydroxyl.
The superior antioxidant qualities of pyritinol also mean that an appropriate pyritinol dosage can combat arthritis and assist neuroprotection. For example, protecting cartilage against free-radical induced degradation may explain why a Pyritinol treatment has proved successful for rheumatoid arthritis. Also, in some cases of stroke and brain trauma, where the generation of hydroxyl free-radicals is abundant, pyritinol has also proved successful.
From the available pyritinol information, it’s also clear that taking pyriothioxine or other commercially available preparations, can improve glucose uptake in the brain, which in turn increases brain cell energy. Pyritinol may also enhance vigilance by increasing nerve activity in an area of the brain called the locus coeruleus; key to physiological responses to stress and helping to control attention, learning and memory.
Other research also reveals pyritinol effects on the immune system by helping neutrophil migration. Neutrophils form part of our first line of defence against bacterial infection, cruising around the blood stream waiting to be signalled (chemotaxis) to a site where damage is happening. Taking pyritinol cerbon 6, pyridoxine disulfate or pyrithioxine can strongly encourage chemotaxis without increasing free radicals.
As part of your anti-ageing program, a single100mg tablet may be taken 1 to 3 times a day. Tablets should not be taken after meals.
For treatment of other specific conditions, your initial dosage could be as much as 2 tablets taken 3 times a day for 10 days. All the available pyritinol information suggests this should be reduced thereafter to 1 tablet, 3 times a day.
Whether you are prescribed pyrithioxine or one of the other commonly available versions, pyritinol is remarkably well tolerated by most people and has few reported side effects.
The one major exception concerns its use for rheumatoid arthritis. According to some pyritinol reviews, side effects in large scale rheumatoid arthritis trials showed “mostly nuisance events” that did not pose health risks and were reversible.
There’s no reliable data available concerning the use of pyrithioxine and other versions of the nootropic during pregnancy or by breast-feeding mothers, so its use isn’t currently recommended.
If you are looking to sharpen your mind, make yourself more agile and healthy, and boost immunity, then consider a daily dose of pyritinol.
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Pyritinol is good for optimal Brain Carbohydrate Metabolism (BCM) and what's good for BCM is good for the brain and the mind
James South MA, Oregon.
I've added Pyritinol to my regime, it's a real smart-drug find!