Spermidine FAQ – All Your Questions Answered!

Written by Anti Aging Systems

Product spotlight - Spermidine

Product spotlight – Spermidine

What is Spermidine?

Spermidine is a natural polyamine found in all cells in the body [1]. Polyamines are compounds created from two or more amino groups; in the case of Spermidine (C 7H 19N 3), Putrescine and Spermine.

What is it good for?

Spermidine has been linked with multiple health benefits including prolonged lifespan. This is in part due to it’s anti-inflammatory and antioxidant properties, as well as its ability to boost cell renewal and autophagy.

What does autophagy mean?

Autophagy is the term used to describe the process in which old/damaged cells are broken down and reused to create new, healthy cells [2]. Illness and aging can both have detrimental effects on the autophagy process, that means this natural “clearing out” process is impacted. This can in turn lead to reduce ability to fight disease, advanced aging and reduced immunity.

Does Spermidine contain actual sperm?

No – although it’s a common question. That being said, Spermidine is found in semen, as it is present in all cells of the body.

Which foods are highest in Spermidine?

There are many plant derived foods with moderate to high levels of Spermidine; these include:

  • Soya beans
  • Wheatgerm
  • Vegetables (peas and mushrooms are both excellent sources) as well as cruciferous veg such as cauliflower or broccoli
  • Cheese (particularly cheddar, brie, parmesan and gouda)
  • Fruits (mangos and bananas particularly so)

Should I supplement with Spermidine?

Spermidine is a naturally occurring product so there are minimal risks associated with taking it in supplement form. Given the benefits it can have on the body and boosting cell renewal, immunity and promoting antiaging, it’s certainly a recommend supplement on our list!

That being said, if you have any doubts or existing health conditions, please check with your health provider first.

Spermidine dosing?

6mg per day is an average dose, but it would be best to check with your health provider if you aren’t sure.

Does Spermidine have side effects?

There are no known side effects associated with taking Spermidine supplements.

Is Spermidine vegan friendly?

Yes, Spermidine is vegan friendly.


  1. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6287690/
  2. https://my.clevelandclinic.org/health/articles/24058-autophagy
  3. https://www.supersmart.com/en/blog/anti-ageing/which-foods-have-the-highest-content-spermidine-s420