 Modafinil increases alertness and concentration
(Alertec / ProVigil / Modiodal)Modafinil is an mind and mood enhancing stimulant that is not addictive, has no side effects and does not affect sleep Modafinil is an eugeroic drug, (which simply means ‘good arousal’). This unique class of drug contains only two at present, Adrafinil and Modafinil. Modafinil is a memory-improving and mood-brightening psychostimulant. It enhances wakefulness and vigilance, but its pharmacological profile is notably different from the amphetamines, methylphenidate (Ritalin) or cocaine. The basis of its uniqueness lies in its ability to stimulate only when stimulation is required. As a result the ‘highs and lows’ associated with other stimulants such as amphetamine are absent. Modafinil does not bring about the anxiety, agitation and insomnia associated with these more familiar stimulants. Normal sleep patterns are not affected, nor is Modafinil addictive or accompanied by the number of side effects present with currently prescribed stimulants. Modafinil induces wakefulness in part by its action in the anterior hypothalamus. It appears to only stimulate alpha-1 brain receptors that are responsible for the uptake of nor-adrenaline. Its dopamine-releasing action is weak and dose-dependent, making the chances of a euphoric response, dose-escalation or becoming tolerant to the drug very unlikely. Modafinil is proving clinically useful in the treatment of narcolepsy, a neurological disorder marked by uncontrollable attacks of daytime sleepiness. Experimentally, Modafinil is also used in the treatment of Alzheimer's disease, depression, attention-deficit disorder, myotonic dystrophy, multiple sclerosis-induced fatigue, post-anaesthesia grogginess, cognitive impairment in schizophrenia, spasticity associated with cerebral palsy, age-related memory decline, idiopathic hypersomnia, jet-lag and everyday cat-napping. Dosage:
Take one 100mg tablet for a period of up-to 8-hours stimulation, once or twice daily. Avoid use in the evening. 
What our customers say...
| To see the full ingredients in Modiodal ®, and its "approved" uses/ dosages, as well as potential side effects and contraindications please click here. To see the full ingredients in Provigil ®, and its "approved" uses/ dosages, as well as potential side effects and contraindications please click here. To see the full ingredients in Alertec ®, and its "approved" uses/ dosages, as well as potential side effects and contraindications please click here. To read articles about Modafinil please click here. To rad our back catalogue of e-news of Modafinil please click here |
| Caution: Modafinil is a controlled substance in Canada and the USA. |
Approved Uses ProvigilPROVIGIL / MODAFINIL Composition Each tablet contains: Active substance: modafinil 100 mg Excipients: monohydrated lactose, corn starch, magnesium silicate, croscarmellose sodium, povidone K90, talc and magnesium stearate. Pharmaceutical form and content Tablets. Box of 30 tablets of 100 mg. Pharmacotherapeutic category Psychostimulant and nootropic agents. The drug acts on the central nervous system to increase the level of vigilance. Therapeutic indications Narcolepsy. Modafinil is effective in reducing excessive diurnal drowsiness associated with this condition. Contraindications Known hypersensitivity to PROVIGIL or to any component of the preparation. The use of PROVIGIL is contraindicated during pregnancy and lactation (see. Special warnings). Precautions for use Patients suffering from anxiety should receive treatment with PROVIGIL at specialist units only. Patients should be advised to inform their doctor in case of potential pregnancy or if they are planning to become pregnant during therapy. In the light of these circumstances, treatment with modafinil should be suspended. In the hypertensive patient, blood pressure and heart rate should be monitored. PROVIGIL tablets should not be administered to patients with a history of left ventricular hypertrophy or with ischaemic ECG changes, chest pain, arrhythmia or other clinically significant manifestation of prolapse of the mitral valve associated with the use of C.N.S. stimulants. Interactions Oral contraceptives: because of the enzyme induction of PROVIGIL, the efficacy of oral contraceptives may be compromised. In case of the use of oral contraceptives, a product containing 50 mg or more of ethinyl oestradiol should be taken. Adequate contraception requires continuation of the oral contraceptive for two cycles after stopping PROVIGIL. Tricyclic antidepressants: in a single dose pharmacokinetic interaction study of PROVIGIL (200 mg) and clomipramine (50 mg), no clinically important alterations were noted in the pharmacokinetic profile of PROVIGIL or clomipramine. Given the limited experience or the concomitant administration of PROVIGIL with this class of drugs, patients receiving these drugs should be carefully monitored. Anti-convulsant therapy: no formal interaction studies of PROVIGIL have been conducted with these drugs and the concomitant administration of these drugs should therefore be undertaken with caution. Special warnings Whilst studies carried out with modafinil and other psychoactive agents have shown a low dependence potential, the possibility of dependence following prolonged use cannot be entirely ruled out. Since the safety and efficacy in controlled studies in children have not been established, the use of PROVIGIL is not recommended in children. Pregnancy and lactation: PROVIGIL is contraindicated for use in pregnancy or during lactation. Effect on the ability to drive and operate machinery: No information is available concerning the effects of PROVIGIL on the ability to drive or operate machinery. Dose, method and time of administration Adults: The recommended daily dose is 200-400 mg. PROVIGIL may be taken as two divided doses in the morning and at noon, or as a single dose in the morning according to physician assessment of the patient and the patient's response. Elderly: There is limited data available on the use of PROVIGIL in elderly patients. Since clearance tends to be reduced with advancing age, it is recommended that patients over 65 years of age should commence therapy at 100 mg daily. In the absence of renal or hepatic impairment, the dose can be subsequently increased to 400 mg/day, depending on response. Renal and hepatic impairment The dose in patients with hepatic or renal impairment should be halved (100-200 mg/day). Overdose The main symptom following massive ingestion is insomnia. Treatment: induced vomiting and gastric lavage should be considered. Hospitalisation and surveillance of psychomotor status, cardiovascular monitoring or surveillance, until the patient's symptoms have resolved. What to do if you forget to take one or more doses of PROVIGIL If you forget to take a dose of PROVIGIL, take the next dose at the usual time. Never take a double dose. Undesirable effects Episodes of a feeling of nervousness, excitation, aggressive tendencies, insomnia, anorexia, headache, CNS stimulation, abdominal pain, dry mouth, palpitations, tachycardia and tremor. Gastrointestinal disorders (nausea, gastric discomfort) have also been reported, usually regressing when tablets are taken during meals. There have also been reports of pruritic skin rashes and, very rarely, cases of buccofacial dyskinesia. Compliance with the instructions in this leaflet will reduce the onset of undesirable effects. Inform your doctor or pharmacist if you experience any undesirable effects not described above. EXPIRY AND STORAGE See the expiry date indicated on the pack; this date refers to the product in its unopened and correctly stored pack. Store the product in a safe and dry place below 25°C; protect from heat sources and sunlight. KEEP OUT OF THE REACH OF CHILDREN Important: do not use the medicine after the expiry date printed on the pack. | The above information is the translation of the manufacturer's insert. It is provided under the supplying company's terms and conditions and should not replace the advice of your personal physician. |
Approved Uses ModiodalMODAFINIL / MODIODAL ® Chemical: Modafinil and excipients- Lactose, corn starch, monosilicate of dehydrated magnesium, sodium croscarmellose polyvidone, talc, magnesium sterate. Recommendations: For the treatment of narcolepsy (with or without cataplexy), idiopathic hypersomnia. Warning: If you are suffering from a heart condition, it is essential that you consult your doctor. Athletes should be aware that one of the main ingredients of this pharmaceutical product would produce a positive result in anti-doping tests. Precautions: Do not use this product if you are pregnant or nursing. Contraception: Use only normal dosage oral contraceptives or other contraceptive devices. Do not use low dosage oral contraceptives. In the event of serious liver diseases, consult your doctor. In order to avoid possible interactions among several pharmaceutical products; do not neglect to inform your doctor concerning any other treatment you might be receiving. Keep this and all other medicines out of the reach of children. Possible Side Effects: As with any other active pharmaceutical product, Modiodal may produce side effects, which can vary in their intensity, depending on the patient's reaction. Should you have any query, do not hesitate to consult your doctor. Directions for Use: Use strictly according to your doctor's instructions. Conditions for Use: This pharmaceutical product has been prescribed for you to treat a specific condition. It should not be used for other purposes. It should not be used except under a doctor's supervision. Another person should not recommend it for use. Expiry Date: Do not use once the expiry date shown clearly on the box has passed. ATHLETES: Athletes please note, the product contains an active ingredient, which could produce a positive dope test result. | The above information is the translation of the manufacturer's insert. It is provided under the supplying company's terms and conditions and should not replace the advice of your personal physician. |
Approved Uses AlertecMODAFINIL / Alertec ® CHEMICAL: Alertec and excipients- Lactose, maize starch, magnesium monosilicate, sodium croscarmellose polyvidone, magnesium stearate and talc. RECOMMENDATIONS: For the treatment of narcolepsy (with or without cataplexy), idiopathic hypersomnia. WARNING: If you are suffering from a heart condition, it is essential that you consult your doctor. Athletes should be aware that one of the main ingredients of this pharmaceutical product would produce a positive result in anti-doping tests. PRECAUTIONS: Do not use this product if you are pregnant or nursing. CONTRACEPTION: Use only normal dosage oral contraceptives or other contraceptive devices. Do not use low dosage oral contraceptives. In the event of serious liver diseases, consult your doctor. In order to avoid possible interactions among several pharmaceutical products; do not neglect to inform your doctor concerning any other treatment you might be receiving. Keep this and all other medicines out of the reach of children. POSSIBLE SIDE EFFECTS: As with any other active pharmaceutical product, Alertec may produce side effects, which can vary in their intensity, depending on the patient’s reaction. Should you have any query, do not hesitate to consult your doctor. DIRECTIONS FOR USE: Use strictly according to your doctor's instructions. CONDITIONS FOR USE: This pharmaceutical product has been prescribed for you to treat a specific condition. It should not be used for other purposes. It should not be used except under a doctor’s supervision. Another person should not recommend it for use. EXPIRY DATE: Do not use once the expiry date shown clearly on the box has passed. ATHLETES: Athletes please note the product contains an active ingredient, which could produce a positive dope test result. | The above information is the translation of the manufacturer's insert. It is provided under the supplying company's terms and conditions and should not replace the advice of your personal physician. |
| 
What will society make of a compound such as Modafinil that is more like caffeine than amphetamine in terms of safety, and yet as effective as the amphetamines?
