Articles by PIERPAOLI, M.D., Walter


  • The Pineal Clock, Cancer and Melatonin

    The pineal clock, cancer and melatonin Cancer and non-cancer; strategies for early detection, prevention and cure of neoplastic processes By Walter Pierpaoli, M.D.   I propose here that cancer, similarly to most diseases such as cardiovascular, autoimmune and neurodegenerative diseases is simply, in most cas...
  • Thyroid deficiencies: The incredible and dangerous confusion

    Dr. Walter Pierpaoli speaks out! Since I graduated in 1960, I have been deeply involved with endocrinology. Hormone functions are basic for body control and they have always attracted my passionate interest. In addition, my focus on the thyroid sharply increased when I developed myself a De Quervain thyroiditis in 1989 and the doctors gave me levothyroxine (T4) to control the resulti...
  • Who Is Afraid Of Health?

    Who Is Afraid Of Health? Known throughout the world for his discoveries related to melatonin, to the pineal gland and to immunological identity, the author openly denounces the obstructionism by the pharmaceutical cartel to accessing really effective therapies for restoring health and preventing the onset of degenerative diseases. Foreword Such an unlikely question finds prompt answers which everyone awaits or senses. These obvious answers are in everyone's mind, b...
  • The rotational theory of aging

    The rotational theory of aging An interview with Walter Pierpaoli, M.D., PhD. In this interview, the Editor of the Aging Matters™ magazine, Phil Micans (PM) interviews Walter Pierpaoli, M.D., Ph.D. (WP) Dr Pierpaoli is famous for his scientific and clinical published research into melatonin, the thymus,...
  • TRH, the life-generating and life-maintaining entity

    TRH, the life-generating and life-maintaining entity A statement from Dr Walter Pierpaoli When I think of the “peptide swamp”, I wonder why should this tiny tripeptide called erroneously and misleadingly “thyrotropin-releasing hormone” (TRH) be classified as a “hormone”. Certainly his discoverer Roger Guillemin would agree with me that in fact, names are given to new molecules with unknown functions then become victims of nomenclature and lose th...
  • The fundamental and largely neglected key role of the thyroid gland

    The fundamental and largely neglected key role of the thyroid gland Its energy-generating, oxygen-producing mechanism After 60 years of lonely meditation within the deafening noise of medical research, I can now assert, for the sake of all doctors who read these, that all diseases can be prevented and, when we are late, at least brought back under control. The main cause of our inability to prevent and cure diseases and aging is...
  • The age-reversing properties of Thyrotropin Releasing Hormone (TRH)

    The age-reversing properties of Thyrotropin Releasing Hormone (TRH) Previous work from our laboratory prompted us to study the effects of short-term, acute administration of TRH or its chronic oral administration, on organs, tissues and aging-related metabolic and hormonal markers, in order to acquire more knowledge on effects, dosage and timing of administration according to its circadia...
  • Dr Pierpaoli Discusses TRH (Thyrotropin Releasing Hormone)

    Dr Walter Pierpaoli Discusses TRH (Thyrotropin Releasing Hormone) It’s Roles and Uses with Patient Examples and Procedures Part OnePart Two ...
  • TRH, resetting and reversing the aging clock

    TRH, resetting and reversing the aging clock (The evidence for a pineal-directed aging program, its control and clinical intervention) The many theories on the nature and origin of aging clearly show that we did not know what is aging and what it means. However, there cannot be many kinds of ‘physiologic’ aging, but only one! The many claims and dissertations of the advocates of many hypotheses on the nature of aging are not supported at all by the ‘hard facts’, name...
  • The TRH miracle!

    The TRH miracle! An interview with Walter Pierpaoli, M.D. Dr. Pierpaoli is a famous medical professional within the antiaging fraternity because of his extensive published research in the fields of aging, cancer and immunity. He has tirelessly relayed this to other health professionals and researchers through his own; ‘Stromboli conference on aging and cancer’ which takes place in Italy every 3 years. He is also known to many members of the publ...
  • Interview with Walter Pierpaoli, M.D. about melatonin and TRH

    Interview with Walter Pierpaoli, M.D. about melatonin and TRH Born in 1934, Dr. Walter Pierpaoli is one of the world’s eminent researchers in the field of aging and cancer. He is perhaps best known for his research in the field of melatonin and its effects on aging, sleep patterns, cancer, jet lag, fertility and immunity (to name a few). His efforts to promote these facts through his scientific and clinical publications and also th...
  • The Pineal Clock And Cancer

    The Pineal Clock And Cancer Abstract Cancer and non-cancer, strategies for early detection, prevention and cure of neoplastic processes - Abstract I propose here that cancer, similarly to most diseases such as cardiovascular, autoimmune and neurodegenerative diseases is simply, in most cases, the final expression of an early or late derangement of central neuro-endocrine-immune control, defined now as ‘immunological surveillance’, leading to a loss of non-prolifera...
  • TRH Thyrotropin-releasing Hormone And Obesity

    TRH Thyrotropin-releasing Hormone And Obesity By Walter Pierpaoli and Vladimir A. Lesnikovb aInterbion Foundation for Basic Biomedical Research, Gordola, SwitzerlandbFred Hutchinson Cancer Research Center, Seattle, WA, USA Abstract Adult adipose mice, high fat diet-fed (HFD) mice, anterior hypothalamus-lesioned obese mice and genetically obese mice, were in...
  • The Essential Cyclicity of Life

    The Essential Cyclicity of Life (The Discovery of the Pineal Life Clock) Ed.- Dr. Pierpaoli is one of the few really serious academic scientists who is interested and determined to pursue anti-aging medicine and prevent aging itself. Indeed, his work speaks for itself, as he is the man who introduced the concept of melatonin to the world through the initial research and his best selling book - The Key of Life ...
  • MELATONIN: The Miracle Molecule

    MELATONIN: The Miracle Molecule What is melatonin? In our bodies, melatonin is the molecule naturally produced within the pineal gland, the glandular organ nestled between the cerebral hemispheres that the great French philosopher Descartes once proposed to be the "seat of the soul." We find melatonin everywhere in the biological world, from unicellular organisms to the vertebrates. Melatonin is the “Master Hormone-Modulating Molecule” but it is misleading...
  • Interview With Walter Pierpaoli M.D., Ph.D.

    Interview With Walter Pierpaoli M.D., Ph.D. Walter Pierpaoli, M.D., is one of the great avant-garde professional researchers and physicians today who are searching for the central cure for aging disorders. He describes himself thus: "I am not a wizard or a sorcerer but simply a man curious of nature and biology who has spent almost 40 well documented years in the merry companionship of mice, waiting for them to teach me how and why we age and die. My main feature i...
  • How to Stop Aging: Melatonin and the Pineal Gland

      How to Stop Aging?   [Ed. Dr. Pierpaoli is one of the world's leading neuroendocrine researchers and it was his work that has made melatonin "common knowledge" throughout the world. However, as you will read in this article, Dr. Pierpaoli's research about melatonin goes far beyond its use just for sleep, jet-lag and as an anti-oxidant. In-fact, Dr. Pierpaoli's ground-breaking work suggests that melatonin is a crucial factor in the treatment for aging it...
  • Melatonin Prolongs Life

    Melatonin Prolongs Life (Ed.- Dr. Pierpaoli would like readers to know that this article has been assembled for people who can appreciate its simplicity, and not for those "experts" whose minds allow no penetration of the simple and smart laws of Nature). Emmy's Story My mother-in-law; Emmy Hugly, living near Lucerne in Switzerland, is now 94 years-old, perfectly healthy and Parkinson-free in the last 15 years, with no intention to give up! Her story ...