Articles under Resveratrol


  • Antioxidant Extends Lifespan

    The National Institute on Aging (NIA) announced the final results of testing from three government labs regarding the patented antioxidant nordihydroguaiaretic acid (NDGA). All three labs agreed that NDGA extended lifespan by a resounding 12% in mice (1) (see Figure 1).Figure 1: The survival plots for m...
  • Updating the Calorie Restriction Mimetics

    Updating the Calorie Restriction Mimetics When I first started writing about Calorie Restriction Mimetics (CRM) 10 years ago, research in this area was at its infancy. Now however, several CRM are well-known and relatively well-accepted agents which imitate the effects of calorie restriction itself. I highlight the fact that these compounds are not merely pills for those who are too lazy to diet, but may be used (under medical supervision) in association with a healthy lifestyle to ...
  • How to Maintain or Even Improve Your Vision as You Age

    How to Maintain or Even Improve Your Vision as You Age Vision may be the most precious of our five senses. Yet most of us may take it for granted...until it begins to deteriorate with age. As we get older we likely need greater amounts of light to perceive details clearly, and reading glasses to discern fine print which would otherwise be fuzzy. Night driving becomes difficult due to sensitivity from bright lights and glare, and it's challenging to visually adapt to the darkness. Th...
  • Exercise Mimetics

    Exercise Mimetics By Marios Kyriazis MD Research into calorie restriction mimetics (drugs which mimic the physiological actions of calorie restriction itself) has opened up interest in other areas, where drugs or compounds may be able to afford the same benefits as the physical action itself. Here, by ‘action’ I mean not only diet, but also exercise or even sex! In a previous IAS publication I discussed calorie restriction mimetics in some detail. Maybe, in the ...
  • mTOR Inhibitors in Cancer, Aging and Health

    mTOR Inhibitors in Cancer, Aging and Health Marios Kyriazis MD When it comes to the regulation of aging mechanisms, one important molecule which has widespread effects is mTOR. This is the acronym of the mechanistic (previously also called ‘mammalian’) Target Of Rapamycin. It is a protein kinase which regulates the proliferation and development of cells. mTOR acts as a central controller in signalling pathways which regulate the survival and function of the cell...
  • War on Cancer part 2 - winning the war

    Winning the War on Cancer In the previous article ‘losing the war on cancer’ I discussed the current failure of chemotherapy to turn the tide of increasing incidence of cancer. I looked at the reasons why this was the case. I discussed the clues from Nature that suggest that the cancer prevention actions of the phyto-nutrients in fruit and vegetables are likely to be due to a range of nutrient-gene interactions and not just an anti-oxidant effect. Specific phyto-nut...
  • War on Cancer part 1 losing the war

    Losing the War on Cancer In 1971, President Richard Nixon announced the War on Cancer and promised a cure by the 1977 bicentennial. In 2009 death rates from cancer are significantly increased and.....no cure is forthcoming! The failure of chemotherapy to control cancer has become apparent even to the oncology establishment. Scientific American featured a recent cover story entitled: “The War on Cancer — it’s Being Lost.” In it, eminent epidemiologist John C. Bailar III...
  • An effective combination of the anti-aging compounds resveratrol, aminoguanidine, vinpocetine and carnosine

    An effective combination of the anti-aging compounds resveratrol, aminoguanidine, vinpocetine and carnosine In order to fight age-related degeneration, many anti-aging physicians and researchers recommend the intake of not one or two agents but a finely tuned combination of several compounds which have a wide spectrum of actions. In this article I am going to discuss my favourite combination of a few selected and pluripotent (i.e. having multiple actions) anti-aging compounds. These...
  • Improving Your Cardiovascular Health And How To Know How Hard Your Arteries Are

    Improving Your Cardiovascular Health And How To Know How Hard Your Arteries Are It’s amazing to think that as long ago as the 17th Century Dr. Thomas Sydenham wrote that; “a man is as old as his artery.”[i] It’s taken the best part of 300 years to prove that he was correct and yet even today arterial health is not as heavily ‘relied upon’ as other cardiovascular markers- for example cholesterol. Perhaps that’s because arterial stiffness measurement has been difficult a...
  • Melatonin A Universal Guardian?

    Melatonin A Universal Guardian? The role of Melatonin in hormonal regulation and ageing has been described and reviewed in an elegant way by Pierpaoli in his book “The Key of Life” (2007). The fact remains that this molecule seems to be Universally conserved across animal but also plant species; this fact alone should draw attention to its likely universal importance.It was named melatonin because of its ability in certain fish, reptiles and amphibians to lighten ski...
  • Resveratrol and Quercetin - Anti Heart and Anti Cancer Dynamic Duo

      Resveratrol and Quercetin - Anti Heart and Anti Cancer Dynamic Duo By James South MA   Heart disease and cancer are the two main causes of death in America and Europe, eventually killing about 2/3 of all adults. For the past 40 years, it has been virtually a dogma of Western medicine that a diet high in saturated fat/cholesterol, and/or a high blood cholesterol level, is the primary cause of heart disease. The high blood cholesterol so typical of West...
  • Synergistic Programs - Cardio & Heart Pack

    Don’t miss a beat when it comes to your heart health Cardiovascular disease remains the number one killer of adults despite the focus of attention it has had in terms of lifestyle, diet and exercise information that has been poured onto the general public in the last decade. Those who are aware of the real problems appreciate that too much focus has been placed onto cholesterol and that other blood markers such as homocysteine, C-reactive protein, HbA1C and triglyceri...
  • Taking Supplements - Have We Got It Wrong

    Taking Supplements - Have We Got It Wrong The great majority, or perhaps all of you, reading this Antiaging Magazine take some nutritional supplements or other natural remedies. And it is very likely that you take these supplements at regular intervals, say once every day, or every 8 hours or whatever. This regularity in taking a certain supplement reflects the current, standard advice given by most medical practitioners and covers every prescription drug, supplement or natura...
  • Calorie Restriction Mimetics

    Calorie Restriction Mimetics The most reliable intervention which consistently increases the life-span of animals is calorie restriction (CR). This intervention does not only extend the 'average life-span' (the average number of years an animal is expected to live), but it also prolongs the 'maximum life-span', which is the maximum number of years a particular species can possibly reach. The maximum life-span of mice is 3 years, while that of chimpanzees is 50 years. The human...
  • Aging and Immunity by James South

    Aging and Immunity We live in a world of entropy. Entropy is the tendency of complex structures to gradually decay or break down with time. Entropy is one of the brute facts of existence. It is "codified" as one of the basic laws of physics: the second law of thermodynamics, which governs both living and inanimate matter. We humans normally call the process of entropy "ageing." The anti-ageing movement is literally an anti-entropy movement. Modern science has discovere...