List of the Main International Publications

List of the main International Publications

Monographs:

1.   Vladimir Kh. Khavinson. Peptides and Ageing. // Neuroendocrinology Letters. - Vol. 23, Suppl. 3, Special Issue. - 2002. - 144 p.

2.   Khavinson V.Kh., Malinin V.V. Gerontological Aspects of Genome Peptide Regulation. // Basel (Switzerland): Karger AG. - 2005. - 104 p.

3.   Khavinson V.Kh. Peptidergic regulation of ageing. // SPb.: Humanistica. - 2009. - 48 p.

Books and Chapters:

1.      Khavinson V.Kh., Morozov V.G., Anisimov V.N. Experimental Studies of the Pineal Gland Preparation Epithalamin. // The Pineal Gland and Cancer. - Bartsch C., Bartsch H., Blask D.E., Cardinali D.P., Hrushesky W.J.M., Mecke D. (Eds.) - Springer-Verlag, Berlin, Heidelberg. - 2001. - P. 294-306.

2.      Anisimov V.N., Khavinson V.Kh. Small Peptide-associated Modulation of Aging and Longevity. // Modulating Aging and Longevity. - Kluwer Academic Publishers (Printed in Great Britain). - Suresh I.S. Rattan (ed.). - 2003. - P. 279-301.

3.      Vladimir N. Anisimov, Vladimir Kh. Khavinson. Pineal peptides as modulators of aging. // Aging interventions and therapies. - World Scientific. - Suresh I.S. Rattan (ed.). - 2005. - P. 127-146.

4.      Khavinson V.Kh., Neroev V.V., Trofimova S.V., Osokina Yu.Yu. Unique method for restoration of retinal functions in case of different diseases. // SPb. - 2011. - 32 p.

Articles:

1.      Dilman V.M., Anisimov V.N., Ostroumova M.N., Khavinson V.Kh., Morozov V.G. Increase in lifespan of rats following polypeptide pineal extract treatment. // Experimental Pathology. – 1979. – Bd. 17, № 9. – P. 539-545.

2.      Dilman V.M., Anisimov V.N., Ostroumova M.N., Morozov V.G., Khavinson V.Kh., Azarova M.A. Study of the Anti-Tumor Effect of Polypeptide Pineal Extract. // Oncology. – 1979. – Vol. 36, № 6. – P. 274-280.

3.      Anisimov V.N., Khavinson V.Kh., Morozov V.G. Carcinogenesis and aging. IV. Effect of low-molecular-weight factors of thymus, pineal gland and anterior hypothalamus on immunity, tumor incidence and life span of C3H/Sn mice. // Mechanisms of Ageing and Development. – 1982. – Vol. 19. – P. 245-258.

4.      Pisarev O.A., Morozov V.G., Khavinson V.Kh., Shataeva L.K., Samsonov G.V. Isolation, physico-chemical and biological properties of the immunity polypeptide bioregulator from thymus. // Chemistry of Peptides and Proteins. – Berlin, New York. – 1982. – Vol. 1. – P. 137-142.

5.      Anisimov V.N., Loktionov A.S., Khavinson V.Kh., Morozov V.G. Effect of low-molecular-weight factors of thymus and pineal gland on life span and spontaneous tumour development in female mice of different age. // Mechanisms of Ageing and Development. – 1989. – Vol. 49. – P. 245-257.

6.      Anisimov V.N., Bondarenko L.A., Khavinson V.Kh. The Pineal Peptides: Interaction with Indoles and the Role in Aging and Cancer. // Neuroendocrinology: New Frontiers. – London, Tübingen. – 1990. – P. 317-325.

7.      Anisimov V.N., Bondarenko L.A., Khavinson V.Kh. Effect of Pineal Peptide Preparation (Epithalamin) on Life Span and Pineal and Serum Melatonin Level in Old Rats. // Annals of New York Academy of Sciences. – 1992. – Vol. 673. – P. 53-57.

8.      Anisimov V.N., Khavinson V.Kh., Morozov V.G. Twenty Years of Study on Effects of Pineal Peptide Preparation: Epithalamin in Experimental Gerontology and Oncology. // Annals of the New York Academy of Sciences. – 1994. – Vol. 719. – P. 483-493.

9.      Alexandrov V.A., Bespalov V.G., Morozov V.G., Khavinson V.Kh., Anisimov V.N. Study of the post-natal effects of chemopreventive agents on ethylnitrosourea-induced transplacental carcinogenesis in rats. II. Influence of low-molecular-weight polypeptide factors from the thymus, pineal gland, bone marrow, anterior hypothalamus, brain cortex and brain white substance. // Carcinogenesis. – 1996. – Vol. 17, № 8. – P. 1931-1934.

10.  Anisimov V.N., Mylnikov S.V., Oparina T.I., Khavinson V.Kh. Effect of melatonin and pineal peptide preparation epithalamin on life span and free radical oxidation in Drosophila melanogaster. // Mechanisms of Ageing and Development. - 1997. - Vol. 97. - P. 81-91.

11.  Morozov V.G., Khavinson V.Kh. Natural and synthetic thymic peptides as therapeutics for immune dysfunction. // Int. J. Immunopharmacology. – 1997. – Vol. 19, № 9/10. – P. 501-505.

12.  Anisimov V.N., Mylnikov S.V., Khavinson V.Kh. Pineal peptide preparation epithalamin increases the lifespan of fruit flies, mice and rats. // Mechanisms of Ageing and Development. – 1998. – Vol. 103. – P. 123-132.

13.  Khavinson V.Kh., Solovieva D.V. New approach to the prophylaxis and treatment of age-related pathology. // Romanian Journal of Gerontology and Geriatrics. – 1998. – Vol. 20, № 1. – P. 28-34.

14.  Anisimov V.N., Khavinson V.Kh., Morozov V.G. Immunomodulatory synthetic dipeptide L-Glu-L-Trp slows down aging and inhibits spontaneous carcinogenesis in rats. // Biogerontology. – 2000. – Vol. 1. – P. 55-59.

15.  Khavinson V.Kh., Anisimov V.N., Zavarzina N.Yu., Zabezhinskii M.A., Zimina O.A., Popovich I.G., Shtylik A.V., Malinin V.V., Morozov V.G. Effect of Vilon on Biological Age and Lifespan in Mice. // Bulletin of Experimental Biology and Medicine. – 2000. – Vol. 130, № 7. – P. 687–690.

16.  Khavinson V.Kh., Izmailov D.M., Obukhova L.K., Malinin V.V. Effect of epitalon on the lifespan increase in Drosophila melanogaster. // Mechanisms of Ageing and Development. – 2000. – Vol. 120. – P. 141-149.

17.  Khavinson V.Kh., Kvetnoii I.M. Peptide Bioregulators Inhibit Apoptosis. // Bulletin of Experimental Biology and Medicine. – 2000. – Vol. 130, № 12. – P. 1175-1176.

18.  Khavinson V.Kh., Morozov V.G., Malinin V.V., Kazakova T.B., Korneva E.A. Effect of Peptide Lys-Glu on Interleukin-2 Gene Expression in Lymphocytes. // Bulletin of Experimental Biology and Medicine. – 2000. – Vol. 130, № 9. – P. 898-899.

19.  Khavinson V.Kh., Myl’nikov S.V. Effect of Epithalone on the Age-Specific Changes in the Time Course of Lipid Peroxidation in Drosophila melanogaster. // Bulletin of Experimental Biology and Medicine. – 2000. – Vol. 130, № 11. – P. 1116-1119.

20.  Khavinson V.Kh., Myl’nikov S.V. Effect of Pineal Tetrapeptide on Antioxidant Defense in Drosophila melanogaster. // Bulletin of Experimental Biology and Medicine. – 2000. – Vol. 129, № 4. – P. 355-356.

21.  Khavinson V.Kh., Popuchiev V.V., Kvetnoii I.M., Yuzhakov V.V., Kotlova L.N. Regulating Effect of Epithalone on Gastric Endocrine Cells in Pinealectomized Rats. // Bulletin of Experimental Biology and Medicine. – 2000. – Vol. 130, № 12. – P. 1169-1171.

22.  Kvetnoy I.M., Reiter R.J., Khavinson V.Kh. Claude Bernard was right: hormones may be produced by “non-endocrine” cells. // Neuroendocrinology Letters. – 2000. – Vol. 21, № 3. – P. 173-174.

23.  Turchaninova L.N., Kolosova L.I., Malinin V.V., Moiseeva A.B., Nozdrachev A.D., Khavinson V.Kh. Effect of Tetrapeptide Cortagen on Regeneration of Sciatic Nerve. // Bulletin of Experimental Biology and Medicine. – 2000. – Vol. 130, № 12. – P. 1172-1174.

24.  Anisimov V.N., Arutjunyan A.V., Khavinson V.Kh. Effects of pineal peptide preparation Epithalamin on free-radical processes in humans and animals. // Neuroendocrinology Letters. – 2001. – Vol. 22, № 1. – P. 9-18.

25.  Anisimov V.N., Khavinson V.Kh., Mikhalski A.I., Yashin A.I. Effect of synthetic thymic and pineal peptides on biomarkers of ageing, survival and spontaneous tumour incidence in female CBA mice. // Mechanisms of Ageing and Development. – 2001. – Vol. 122, № 1. – P. 41-68.

26.  Khavinson V.Kh. Tissue-Specific Effects of Peptides. // Bulletin of Experimental Biology and Medicine. - 2001. - Vol. 132, № 2. - P. 807-808.

27.  Khavinson V., Goncharova N., Lapin B. Synthetic tetrapeptide epitalon restores disturbed neuroendocrine regulation in senescent monkeys. // Neuroendocrinology Letters. - 2001. - Vol. 22, № 4. - P. 251-254.

28.  Khavinson V.Kh., Konovalov S.S., Yuzhakov V.V., Popuchiev V.V., Kvetnoi I.M. Modulating Effects of Epithalamin and Epithalon on the Functional Morphology of the Spleen in Old Pinealectomized Rats. // Bulletin of Experimental Biology and Medicine. – 2001. – Vol. 132, № 5. – P. 1116-1120.

29.  Khavinson V.Kh., Myl’nikov S.V., Oparina T.I., Arutyunyan A.V. Effects of Peptides on Generation of Reactive Oxygen Species in Subcellular Fractions of Drosophila melanogaster. // Bulletin of Experimental Biology and Medicine. – 2001. – Vol. 132, № 1. – P. 682-685.

30.  Khavinson V.Kh., Timofeeva N.M.,  Malinin V.V., Egorova V.V., Nikitina A.A. Effect of the Dipeptide Vilon on Activity of Digestive Enzyme in Rats of Various Ages. // Bulletin of Experimental Biology and Medicine. – 2001. – Vol. 131, № 6. – P. 583-585.

31.  Khavinson V.Kh., Yakovleva N.D., Popuchiev V.V., Kvetnoi I.M., Manokhina R.P. Reparative Effect of Epithalon on Pineal Gland Ultrastructure in g-Irradiated Rats. // Bulletin of Experimental Biology and Medicine. – 2001. – Vol. 131, № 1. – P. 81-85.

32.  Khavinson V.Kh., Yuzhakov V.V., Kvetnoi I.M., Malinin V.V., Popuchiev V.V., Fomina N.K. Immunohistochemical and Morphometric Analysis of Effects of Vilon and Epithalon on Functional Morphology of Radiosensitive Organs. // Bulletin of Experimental Biology and Medicine. – 2001. – Vol. 131, № 3. – P. 285-292.

33.  Pliss G.B., Mel’nikov A.S., Malinin V.V., Khavinson V.Kh. Inhibitory Effect of Peptide Vilon on the Development of Induced Rat Urinary Bladder Tumors in Rats. // Bulletin of Experimental Biology and Medicine. – 2001. – Vol. 131, № 6. – P. 558-560.

34.  Anisimov S.V., Bokheler K.R., Khavinson V.Kh., Anisimov V.N. Studies of the Effects of Vilon and Epithalon on Gene Expression in Mouse Heart using DNA-Microarray Technology. // Bulletin of Experimental Biology and Medicine. – 2002. – Vol. 133, № 3. – P. 293-299.

35.  Anisimov V.N., Khavinson V.Kh., Alimova I.N., Provintsiali M., Manchini R., Francheski K. Epithalon Inhibits Tumor Growth and Expression of HER-2/neu Oncogene in Breast Tumors in Transgenic Mice Characterized by Accelerated Aging. // Bulletin of Experimental Biology and Medicine. – 2002. – Vol. 133, № 2. – P. 167-170.

36.  Anisimov V.N., Khavinson V.Kh., Alimova I.N., Semchenko A.V., Yashin A.I. Epithalon Decelerates Aging and Suppresses Development of Breast Adenocarcinomas in Transgenic HER-2/neu Mice. // Bulletin of Experimental Biology and Medicine. – 2002. – Vol. 134, № 2. – P. 187-190.

37.  Anisimov V.N., Khavinson V.Kh., Popovich I.G., Zabezhinski M.A. Inhibitory effect of peptide Epitalon on colon carcinogenesis induced by 1,2-dimethylhydrazine in rats. // Cancer Letters. – 2002. – Vol. 183. – P. 1-8.

38.  Anisimov V.N., Khavinson V.Kh., Provinciali M., Alimova I.N., Baturin D.A., Popovich I.G., Zabezhinski M.A., Imyanitov E.N., Mancini R., Franceschi C. Inhibitory effect of the peptide epitalon on the development of spontaneous mammary tumors in HER-2/NEU transgenic mice. // Internaional Journal of Cancer. – 2002. – Vol. 101. – P. 7-10.

39.  Goncharova N.D., Lapin B.A., Khavinson V.Kh. Age-Associated Endocrine Dysfunctions and Approaches to Their Correction. // Bulletin of Experimental Biology and Medicine. – 2002. – Vol. 134, № 5. – P. 417-421.

40.  Khavinson V.Kh., Egorova V.V., Timofeeva N.M., Malinin V.V., Gordova L.A., Gromova L.V. Effect of Vilon and Epithalon on Glucose and Glycine Absorption in Various Regions of Small Intestine in Aged Rats. // Bulletin of Experimental Biology and Medicine. – 2002. – Vol. 133, № 5. – P. 494-496.

41.  Khavinson V.Kh., Korneva E.A., Malinin V.V., Rybakina E.G., Pivanovich I.Yu., Shanin S.N. Effect of Epitalon on Interleukin-1ß Signal Transduction and the Reaction of Thymocyte Blast Transformation Under Stress. // Neuroendocrinology Letters. – 2002. – Vol. 23, № 5/6. – P. 411-416.

42.  Khavinson V.Kh., Lezhava T.A., Monaselidze J.G., Dzhokhadze T.A., Dvalishvili N.A., Bablishvili N.K., Ryadnova I.Yu. Effects of Livagen Peptide on Chromatin Activation in Lymphocytes from Old People. // Bulletin of Experimental Biology and Medicine. – 2002. – Vol. 134, № 4. – P. 389-392.

43.  Khavinson V.Kh., Malinin V.V. Mechanisms Underlying Geroprotective Effects of Peptides. // Bulletin of Experimental Biology and Medicine. – 2002. – Vol. 133, № 1. – P. 1-5.

44.  Khavinson V.Kh., Malinin V.V., Timofeeva N.M., Egorova V.V., Nikitina A.A. Effects of Epithalon on Activities Gastrointestinal Enzymes in Young and Old Rats. // Bulletin of Experimental Biology and Medicine. – 2002. – Vol. 133, № 3. – P. 290-292.

45.  Khavinson V.Kh., Malinin V.V., Trofimova S.V., Zemchikhina V.N. Inductive Activity of Retinal Peptides. // Bulletin of Experimental Biology and Medicine. – 2002. – Vol. 134, № 5. – P. 482-484.

46.  Khavinson V.Kh., Razumovskii M.I., Trofimova S.V., Grigor’yan R.A., Chaban T.V., Oleinik T.L., Razumovskaya A.M. Effect of Epithalon on Age-Specific Changes in the Retina in Rats with Hereditary Pigmentary Dystrophy. // Bulletin of Experimental Biology and Medicine. – 2002. – Vol. 133, № 1. – P. 87-89.

47.  Khavinson V., Razumovsky M., Trofimova S., Grigorian R., Razumovskaya A. Pineal-regulating tetrapeptide epitalon improves eye retina condition in retinitis pigmentosa. // Neuroendocrinology Letters. – 2002. – Vol. 23, № 4. – P. 365-368.

48.  Khavinson V.Kh., Rybakina E.G., Malinin V.V., Pivanovich I.Yu., Shanin S.N., Korneva E.A. Effects of Short Peptides on Thymocyte Blast Transformation and Signal Transduction along the Sphingomyelin Pathway. // Bulletin of Experimental Biology and Medicine. – 2002. – Vol. 133, № 5. – P. 497-499.

49.  Khavinson V.Kh., Timofeeva N.M., Malinin V.V., Gordova L.A., Nikitina A.A. Effect of Vilon and Epithalon on Activity of Enzymes in Epithelial and Subepithelial Layers in Small Intestine of Old Rats. // Bulletin of Experimental Biology and Medicine. – 2002. – Vol. 134, № 6. – P. 562-564.

50.  Khlystova Z.S., Kalinina I.I., Khavinson V.Kh. Thymic Hormones in Human Fetal Skin Epidermis. // Bulletin of Experimental Biology and Medicine. – 2002. – Vol. 133, № 2. – P. 196-198.

51.  Rosenfeld S.V., Togo E.F., Mikheev V.S., Popovich I.G., Zabezhinskii A.M., Khavinson V.Kh., Anisimov V.N. Effect of Epithalon on the Incidence of Chromosome Aberrations in Senescence-Accelerated Mice. // Bulletin of Experimental Biology and Medicine. – 2002. – Vol. 133, № 3. – P. 274-276.

52.  Sibarov D.A., Kovalenko R.I., Malinin V.V., Khavinson V.Kh. Epitalon influences pineal secretion in stress-exposed rats in the daytime. // Neuroendocrinology Letters. – 2002. – Vol. 23, № 5/6. – P. 452-454.

53.  Anisimov V.N., Khavinson V.Kh., Popovich I.G., Zabezhinski M.A., Alimova I.N., Rosenfeld S.V., Zavarzina N.Yu., Semenchenko A.V., Yashin A.I. Effect of Epitalon on biomarkers of aging, life span and spontaneous tumor incidence in female Swiss-derived SHR mice. // Biogerontology. – 2003. – № 4. – P. 193-202.

54.  Khavinson V.Kh., Bondarev I.E., Butyugov A.A. Epithalon Peptide Induces Telomerase Activity and Telomere Elongation in Human Somatic Cells. // Bulletin of Experimental Biology and Medicine. – 2003. – Vol. 135, № 6. – P. 590-592.

55.  Khavinson V.Kh, Lezhava T.A., Monaselidze J.R., Jokhadze T.A., Dvalis N.A., Bablishvili N.K., Trofimova S.V. Peptide Epitalon activates chromatin at the old age. // Neuroendocrinology Letters. – 2003. – Vol. 24, № 5 – P. 329-333.

56.  Khavinson V.Kh., Morozov V.G. Peptides of pineal gland and thymus prolong human life. // Neuroendocrinology Letters. – 2003. – Vol. 24, № 3/4. – P. 233-240.

57.  Khavinson V.Kh., Razumovsky M.I., Trofimova S.V., Razumovskaya A.M. Retinoprotective Effect of Epithalon in Campbell Rats of Various Ages. // Bulletin of Experimental Biology and Medicine. – 2003. – Vol. 135, № 5. – P. 495-498.

58.  Khavinson V.Kh., Shataeva L.K., Chernova A.A. Effect of Regulatory Peptides on Gene Transcription. // Bulletin of Experimental Biology and Medicine. – 2003. – Vol. 136, № 3. – P. 288-290.

59.  Khavinson V.Kh., Zemchikhina V.N., Trofimova S.V., Malinin V.V. Effect of Peptides on Proliferative Activity of Retinal and Pigmented Epithelial Cells. // Bulletin of Experimental Biology and Medicine. – 2003. – Vol. 135, № 6. – P. 597-599.

60.  Kossoy G., Zandbank J., Tendler E., Anisimov V., Khavinson V., Popovich I., Zabezhinski M., Zusman I., Ben-Hur H. Epitalon and colon carcinogenesis in rats: Proliferative activity and apoptosis in colon tumors and  mucosa. // International Journal of Molecular Medicine. – 2003. – Vol. 12, № 4. – P. 473-477.

61.  Ryzhak G.A., Nekrasov P.A., Kiselev O.I., Khavinson V.Kh. Study of Protein Components of Natural Peptide Regulators. // Bulletin of Experimental Biology and Medicine. – 2003. – Vol. 135, № 1. – P. 52-54.

62.  Tutel’yan V.A., Khavinson V.Kh., Malinin V.V. Physiological Role of Short Peptides in Nutrition. // Bulletin of Experimental Biology and Medicine. – 2003. – Vol. 135, № 1. – P. 1-5.

63.  Anisimov S.V., Boheler K.R., Khavinson V.Kh., Anisimov V.N. Elucidation of the effect of brain cortex tetrapeptide Cortagen on gene expression in mouse heart by microarray. // Neuroendocrinology Letters. – 2004. – Vol. 25, № 1/2. – P. 87-93.

64.  Anisimov S.V., Khavinson V.Kh, Anisimov V.N. Effect of Melatonin and Tetrapeptide on Gene Expression in Mouse Brain. // Bulletin of Experimental Biology and Medicine. – 2004. – Vol. 137, № 5. – P. 504-509.

65.  Goncharova N.D., Vengerin A.A., Khavinson V.Kh, Lapin B.A. Peptide Correction of Age-Related Hormonal Dysfunction of the Pancreas in Monkeys. // Bulletin of Experimental Biology and Medicine. – 2004. – Vol. 138, № 7. – P. 80-83.

66.  Khavinson V.Kh, Bondarev I.E, Butyugov A.A., Smirnova T.D. Peptide Promotes Overcoming of the Division Limit in Human Somatic Cell. // Bulletin of Experimental Biology and Medicine. – 2004. – Vol. 137, № 5. – P. 613-616.

67.  Khavinson V.Kh, Lezhava T.A., Malinin V.V. Effects of Short Peptides on Lymphocyte Chromatin in Senile Subjects. // Bulletin of Experimental Biology and Medicine. – 2004. – Vol. 137, № 1. – P. 78-81.

68.  Korkushko O.V., Khavinson V.Kh., Shatilo V.B., Magdich L.V. Effect of Peptide Preparation Epithalamin on Circadian Rhythm of Epiphyseal Melatonin-Producing Function in Elderly People. // Bulletin of Experimental Biology and Medicine. – 2004. – Vol. 137, № 4. – P. 389-391.

69.  Labunets I.F., Butenko G.M., Khavinson V.Kh. Effects of Bioactive Factors of the Pineal Gland on Thymus Function and Cell Composition of the Bone Marrow and Spleen in Mice of Different Age. // Bulletin of Experimental Biology and Medicine. – 2004. – Vol. 137, № 5. – P. 620-622.

70.  Labunets I.F., Butenko G.M., Magdich L.V., Korkushko O.V., Khavinson V.Kh., Shatilo V.B. Effect of Epithalamin on Circadian Relationship between the Endocrine Function of the Thymus and Melatonin-Producing Function of the Pineal Gland in Elderly People. // Bulletin of Experimental Biology and Medicine. – 2004. – Vol. 137, № 5. – P. 617-619.

71.  Lezhava T., Khavinson V., Monaselidze J., Jokhadze T., Dvalishvili N., Bablishvili N., Barbakadze S. Bioregulator Vilon-induced reactivation of chromatin in cultured lymphocytes from old people. // Biogerontology. - 2004. - № 5. - P. 73-79.

72.  Raikhlin N.T., Bukaeva I.A., Smirnova E.A., Yarilin A.A., Sharova N.I., Mitneva M.M., Khavinson V.Kh., Polyakova V.O., Trofimov A.V., Kvetnoi I.M. Expression of Argyrophilic Proteins in the Nucleolar Organizer Regions of Human Thymocytes and Thymic Epitheliocytes under Conditions of Coculturing with Vilon and Epithalon Peptides. // Bulletin of Experimental Biology and Medicine. – 2004. – Vol. 137, № 6. – P. 588-591.

73.  Goncharova N.D., Vengerin A.A., Khavinson V.Kh., Lapin B.A. Pineal peptides restore the age-related disturbances in hormonal functions of the pineal gland and the pancreas. // Experimental Gerontology. – 2005. – Vol. 40. – P. 51-57.

74.  Khavinson V.Kh. Effect of Tetrapeptide on Insulin Biosynthesis in Rats with Alloxan-Induced Diabetes. // Bulletin of Experimental Biology and Medicine. – 2005. – Vol. 140, № 4. – P. 452-454.

75.  Khavinson V., Shataeva L., Chernova A. DNA double-helix binds regulatory peptides similarly to transcription factors. // Neuroendocrinology Letters. – 2005. – Vol. 26, № 3. – P. 237-241.

76.  Barabanova S.V., Artyukhina Z.E., Kazakova T.B., Khavinson V.Kh., Malinin V.V., Korneva E.A. Interleukin-2 Concentration in Hypothalamic Structures of Rats Receiving Peptides during Mild Stress. // Bulletin of Experimental Biology and Medicine. - 2006. - Vol. 141, № 4. - P. 390-393.

77.  Khavinson V.Kh., Solovyov A.Yu., Shataeva L.K. Molecular Mechanism of Interaction between Oligopeptides and Double-Stranded DNA. // Bulletin of Experimental Biology and Medicine. – 2006. – Vol. 141, № 4. – P. 457-461.

78.  Korkushko O.V., Khavinson V.Kh., Shatilo V.B., Antonyuk-Shcheglova I.A. Geroprotective Effect of Epithalamine (Pineal Gland Peptide Preparation) in Elderly Subjects with Accelerated Aging. // Bulletin of Experimental Biology and Medicine. – 2006. – Vol. 142, № 3. – P. 356-359.

79.  Khavinson V.Kh., Gavrisheva N.A., Malinin V.V., Chefu S.G., Trofimov E.L. Effect of Pancragen on Blood Glucose Level, Capillary Permeability and Adhesion in Rats with Experimental Diabetes Mellitus.  // Bulletin of Experimental Biology and Medicine. – 2007. – Vol. 144, № 4. – P. 559-562.

80.  Kozina L.S., Arutjunyan A.V., Khavinson V.Kh. Antioxidant properties of geroprotective peptides of the pineal gland. // Archives of Gerontology and Geriatrics. – 2007. – Suppl. 1. – P. 213-216.

81.  Vinogradova I.A., Bukalev A.V., Zabezhinski M.A., Semenchenko A.V., Khavinson V.Kh., Anisimov V.N.  Effect of Ala-Glu-Asp-Gly Peptide on Life Span and Development of Spontaneous Tumors in Female Rats Exposed to Different Illumination Regimes. // Bulletin of Experimental Biology and Medicine. – 2007. – Vol. 144, № 6. – P. 825-830.

82.  Khavinson V.Kh., Solovyov A.Yu., Shataeva L.K. Melting of DNA Double Strand after Binding to Geroprotective Tetrapeptide. // Bulletin of Experimental Biology and Medicine. – 2008. – Vol. 146, № 5. – P. 624-626.

83.  Vinogradova I.A., Bukalev A.V., Zabezhinski M.A., Semenchenko A.V., Khavinson V.Kh., Anisimov V.N.  Geroprotective Effect of Ala-Glu-Asp-Gly Peptide in Male Rats Exposed to Different Illumination. // Bulletin of Experimental Biology and Medicine. – 2008. – Vol. 145, № 4. – P. 472-477.

84.  Khavinson V.Kh., Anisimov V.N. Peptide Regulation of Aging: 35-Year Research Experience. // Bulletin of Experimental Biology and Medicine. - 2009. - Vol. 148, № 1. - P. 94-98.

85.  Anisimov V.N., Khavinson V.Kh. Peptide bioregulation of aging: results and prospects. // Biogerontology. – 2010. – Vol. 11, № 2. – P. 139-149.

86.  Khavinson V.Kh., Gapparov M.M.-G., Sharanova N.E., Vasilyev A.V., Ryzhak G.A. Study of Biological Activity of Lys-Glu-Asp-Trp-NH2 Endogenous Tetrapeptide. // Bulletin of Experimental Biology and Medicine. - 2010. - Vol. 149, № 3. - P. 351-353.

87.  Fedoreyeva L.I., Kireev I.I., Khavinson V.Kh., Vanyushin B.F. Penetration of Short Fluorescence-Labeled Peptides into the Nucleus in HeLa Cells and in vitro Specific Interaction of the Peptides with Deoxyribooligonucleotides and DNA. // Biochemistry. - 2011. - Vol. 76, № 11. - P. 1210-1219.

88.  Khavinson V.Kh., Fedoreeva L.I., Vanyushin B.F. Short Peptides Modulate the Effect of Endonucleases of Wheat Seedling. // Doklady Biochemistry and Biophysics. - 2011. - Vol. 437, № 1. - P. 64-67.

89.  Khavinson V.Kh., Fedoreeva L.I., Vanyushin B.F. Site-Specific Binding of Short Peptides with DNA Modulated Eukaryotic Endonuclease Activity. // Bulletin of Experimental Biology and Medicine. - 2011. - Vol. 151, № 1. - P. 66-70.

90.  Khavinson V.Kh., Linkova N.S., Chalisova N.I., Dudkov A.V., Koncevaya E.A. Effect of Short Peptides on Expression of Signaling Molecules in Organotypic Pineal Cell Culture. // Bulletin of Experimental Biology and Medicine (Cell Technologies in Biology and Medicine). - 2011. - № 3, November. - P. 138-141.

91.  Khavinson V.Kh., Linkova N.S., Polyakova V.O., Dudkov A.V., Kvetnoy I.M. Age-Specific Dynamics of Human Thymus Immune Cell Differentiation. // Bulletin of Experimental Biology and Medicine. - 2011. - Vol. 151, № 5. - P. 631-633.

92.  Khavinson V.Kh., Lin’kova N.S., Trofimov A.V., Polyakova V.O., Sevost’yanova N.N., Kvetnoy I.M. Morphofunctional Fundamentals for Peptide Regulation of Aging. // Biology Bulletin Reviews. - 2011. - Vol. 1, № 4. - P. 390-394.

93. Khavinson V.Kh., Nikolsky I.S., Nikolskaya V.V., Zubov D.A., Galickaya S.N., Taranuha L.I., Semenova Ya.-M.A., Lisica N.A., Linkova N.S., Butenko G.M. Effect of Tripeptides on Lymphoid and Stem Cells. // Bulletin of Experimental Biology and Medicine. - 2011. - Vol. 151, № 6. - P. 722-725.

94.  Khavinson V.Kh., Polyakova V.O., Linkova N.S., Dudkov A.V., Kvetnoy I.M. Peptides Regulate Cortical Thymocytes Differentiation, Proliferation, and Apoptosis. // Journal of Amino Acids. - 2011. - Vol. 2011. - P. 1-5.

95.  Khavinson V., Ribakova Y., Kulebiakin K., Vladychenskaya E., Kozina L., Arutjunyan A., Boldyrev A. Pinealon Increases Cell Viability by Suppression of Free Radical Levels and Activating Proliferative Processes. // Rejuvenation Research. - 2011. - Vol. 14, № 5. - P. 535-541.

96.  Korkushko O.V., Khavinson V.Kh., Shatilo V.B., Antonyk-Sheglova I.A. Peptide Geroprotector from the Pineal Gland Inhibits Rapid Aging of Elderly People: Results of 15-Year Follow-Up. // Bulletin of Experimental Biology and Medicine. - 2011. - Vol. 151, № 3. - P. 366-369.

97.  Korkushko O.V., Khavinson V.Kh., Shatilo V.B., Antonyk-Sheglova I.A., Bondarenko E.V. Prospects of Using Pancragen for Correction of Metabolic Disorders in Elderly People. // Bulletin of Experimental Biology and Medicine. - 2011. - Vol. 151, № 4. - P. 454-456.

98.  Linkova N.S., Khavinson V.Kh., Chalisova N.I., Katanugina A.S., Koncevaya E.A. Peptidergic Stimulation of Differentiation of Pineal Immune Cells. // Bulletin of Experimental Biology and Medicine (Cell Technologies in Biology and Medicine). - 2011. - № 3, November. - P. 124-127.

99. Lin’kova N.S., Polyakova V.O., Trofimov A.V., Kvetnoy I.M., Khavinson V.Kh. Peptidergic Regulation of Thymocyte Differentiation, Proliferation, and Apoptosis during Aging of the Thymus. // Bulletin of Experimental Biology and Medicine. - 2011. - Vol. 151, № 2. - P. 239-242.

100. Monaselidze J.R., Khavinson V.Kh., Gorgoshidze M.Z., Khachidze D.G., Lomidze E.M., Jokhadze T.A., Lezhava T.A. Effect of the Peptide Bronchogen (Ala-Asp-Glu-Leu) on DNA Thermostability. // Bulletin of Experimental Biology and Medicine. - 2011. - Vol. 150, № 3. - P. 375-377.

101. Polyakova V.O., Linkova N.S., Kvetnoy I.M., Khavinson V.Kh. Functional Unity of the Thymus and Pineal Gland and Study of the Mechanisms of Aging. // Bulletin of Experimental Biology and Medicine. - 2011. - Vol. 151, № 5. - P. 627-630.

102.          Solov’ev A.Yu., Morozova P.Yu., Chernova I.A., Chalisova N.I., Shataeva L.K., Zakutskii A.N., Khavinson V.Kh. Extraction and Activity of Regulatory Peptide from Sea Urchin Eggs. // Pharmaceutical Chemistry Journal. - 2011. - Vol. 44, № 11. - P. 601-603.

103.          Arutjunyan A., Kozina L., Stvolinskiy S., Bulygina Y., Mashkina A., Khavinson V. Pinealon prorects the rat offspring from prenatal hyperhomocysteinemia. // International Journal of Clinical Experimental Medicine. - 2012. - Vol. 5, № 2. - P. 179-185.

104.          Chalisova N.I., Lopatina N.G., Kamishev N.G., Linkova N.S., Koncevaya E.A., Dudkov A.V., Kozina L.S., Khavinson V.Kh., Titkov Yu.S. Effect of Tripeptide Lys-Glu-Asp on Physiological Activity of Neuroimmunoendocrine System Cells. // Bulletin of Experimental Biology and Medicine (Cell Technologies in Biology and Medicine). - 2012. - № 2, August. - P. 569-572.

105. Khavinson V.Kh., Lin’kova N.S., Dudkov A.V., Polyakova V.O., Kvetnoi I.M. Peptidergic Regulation of Expression of Genes Encoding Antioxidant and Anti-Inflammatory Proteins. // Bulletin of Experimental Biology and Medicine. - 2012. - Vol. 152, № 5. - P. 615-618.

106.          Khavinson V.Kh., Linkova N.S., Kvetnoy I.M., Kvetnaia T.V., Polyakova V.O., Korf H.-W. Molecular Cellular Mechanisms of Peptide Regulation of Melatonin Synthesis in Pinealocyte Culture. // Bulletin of Experimental Biology and Medicine. - 2012. - Vol. 153, № 2. - P. 255-258.

107. Khavinson V.Kh., Linkova N.S., Polyakova V.O., Kheifets O.V., Tarnovskaya S.I., Kvetnoi I.M. Peptides Tissue-Specifically Stimulate Cell Differentiation during Their Aging. // Bulletin of Experimental Biology and Medicine (Cell Technologies in Biology and Medicine). - 2012. - № 1, May. - P. 148-151.

108.          Khavinson V.Kh., Lin’kova N.S., Polyakova V.O., Kvetnoi I.M., Benberin V.V., D’yakonov M.M., Titkov Yu.S. Tetrapeptide H-Ala-Glu-Asp-Arg-OH Stimulates Expression of Cytoskeletal and Nuclear Matrix Proteins. // Bulletin of Experimental Biology and Medicine (Cell Technologies in Biology and Medicine). - 2012. - № 2, August. - P. 559-562.

109.          Khavinson V.Kh., Linkova N.S., Pronyaeva V.E., Chalisova N.I., Koncevaya E.A., Polyakova V.O., Kvetnaya T.V., Kvetnoy I.M., Yakovlev G.M. A Method of Creating a Cell Monolayer Based on Organotypic Culture for Screening of Physiologically Active Substances. // Bulletin of Experimental Biology and Medicine. - 2012. - Vol. 153 № 5 - P. 795-799.

110.          Khavinson V.Kh., Malinin V.V., Vanyushin B.F. Role of Peptides in Epigenetic Regulation of Gene Activities in Ontogeny. // Bulletin of Experimental Biology and Medicine. - 2012. - Vol. 152 № 4 - P. 470-474.

111.          Khavinson V.Kh., Solov’ev A.Yu., Zhilinskii D.V., Shataeva L.K., Vanyushin B.F. Epigenetic Aspects of Peptide-Mediated Regulation of Aging. // Advances in Gerontology. - 2012. - Vol. 2, № 4. - P. 277-286.

112.          Linkova N.S., Katanugina A.S., Khavinson V.Kh. Expression of AIF and CGRP Markers in Epiphysis and Thymus during Aging. // Advances in Gerontology. - 2012. - Vol. 2, № 3. - P. 230-233.

113. Zamorskii I.I., Sopova I.Yu., Khavinson V.Kh. Effect of Melatonin and Epithalamin on the Content of Protein and Lipid Peroxidation Products in Rat Cortex and Hippocampus under Conditions of Acute Hypoxia. // Bulletin of Experimental Biology and Medicine. - 2012. - Vol. 154 № 1 - P. 51-53.

114. Berrut G., Andrieu S., Araujo de Carvalho I., Baeyens J.P., Bergman H., Cassim B., Cerreta F., Cesari M., Cha H.B., Chen L.K., Cherubini A., Chou M.Y., Cruz-Jentoft A.J., L.de Decker, Du P., Forette B., Forette F., Franco A., Guimaraes R., Gutierrez-Robledo L.M., Jauregui J., Khavinson V., Lee W.J., Peng L.N., Perret-Guillaume C., Petrovic M., Retornaz F., Rockwood K., Rodriguez-Manas L., Sieber C., Spatharakis G., Theou O., Topinkova E., Vellas B., Benetos A. Promoting access to innovation for frail old persons. // The Journal of Nutrition, Health & Aging. - 2013. - Vol. 17, № 8. - P. 688-693.

115. Calisova N.I., Konsevaya N.E., Linkova N.S., Pronyaeva V.E., Chervyakova N.A., Umnov R.S., Benberin V.V., Khavinson V.Kh. Biological Activity of Amino Acids in Organotypic Tissue Cultures. // Bulletin of Experimental Biology and Medicine (Cell Technologies in Biology and Medicine). - 2013. - Vol. 155, № 4. - P. 581-585.

116.          Fedoreeva L.I., Smirnova T.A., Kolomijtseva G.Ya., Khavinson V.Kh., Vanyushin B.F. Interaction of Short Peptides with FITC-Labeled Wheat Histones and Their Complexes with Deoxyribooligonucleotides. // Biochemistry (Moscow). - 2013. - Vol. 78, № 2. - P. 166-175.

117.          Khavinson V.Kh., Durnova A.O., Polyakova V.O., Tolibova G.H., Linkova N.S., Kvetnoy I.M., Kvetnaia T.V., Tarnovskaya S.I. Effects of Pancragen on the Differentiation of Pancreatic Cells During Their Ageing. // Bulletin of Experimental Biology and Medicine. - 2013. - Vol. 154 № 4 - P. 501-504.

118.          Khavinson V.Kh., Kuznik B.I., Ryzhak G.A. Peptide Bioregulators: A New Class of Geroprotectors. Message 1: Results of Experimental Studies. // Advances in Gerontology. - 2013. - Vol. 3, № 3. - P. 225-235.

119.          Khavinson V.Kh., Pronyaeva V.E., Linkova N.S., Trofimova S.V. Peptidergic Regulation of Differentiation of Embryonic Retinal Cells. // Bulletin of Experimental Biology and Medicine (Cell Technologies in Biology and Medicine). – 2013. – Vol. 1, № 1. – P. 172-174.

120.          Khavinson V.Kh., Sevostyanova N.N., Durnova A.O., Linkova N.S., Tarnovskaya S.I., Dudkov A.V., Kvetnaya T.V. Tetrapeptide Stimulates Functional Activity of Pancreatic Cells in Aging. // Advances in Gerontology. - 2013. - Vol. 3, № 3. - P. 220-224.

121. Khavinson V.Kh., Solov’ev A.Yu., Tarnovskaya S.I., Lin’kova N.S. Mechanism of Biological Activity of Short Peptides: Cell Penetration and Epigenetic Regulation of Gene Expression. // Biology Bulletin Reviews. - 2013. - Vol. 3, № 6. - P. 451-455.

122. Khavinson V.Kh., Tarnovskaya S.I., Linkova N.S., Pronyaeva V.E., Shataeva L.K., Yakutseni P.P. Short Cell-Penetrating Peptides: A Model of Interactions with Gene Promoter Sites. // Bulletin of Experimental Biology and Medicine. - 2013. - Vol. 154 № 3 - P. 403-408.

123. Kuznik B.I., Linkova N.S., Tarnovskaya S.I., Khavinson V.Kh. Cytokinis and Regulatory Peptides: Age-Related Changes, Atherosclerosis, and Thrombotic Diseases. // Advances in Gerontology. - 2013. - Vol. 3, № 4. - P. 243-254.

124. Lin’kova N.S., Kuznik B.I., Khavinson V.Kh. The Peptide Ala-Glu-Asp-Gly and Interferon Gamma: Their Role in Immune Response during Aging. // Advances in Gerontology. - 2013. - Vol. 3, № 2. - P. 124-128.

125. Sevostianova N.N., Linkova N.S., Polyakova V.O., Chervyakova N.A., Kostylev A.V., Durnova A.O., Kvetnoy I.M., Abdulragimov R.I., Khavinson V.Kh. Immunomodulating Effects of Vilon and Its Analogue in the Culture of Human and Animal Thymus Cells. // Bulletin of Experimental Biology and Medicine (Cell Technologies in Biology and Medicine). - 2013. - Vol. 154 № 4. - P. 562-565.

126. Vakhitov T.Ya., Chalisova N.I., Polevaya E.V., Linkova N.S., Khavinson V.Kh. Regulatory Functions of Amino Acids and Their Combinations in Prokaryotes and Tissues of Higher Organisms. // Biology Bulletin Reviews. - 2013. - Vol. 3, № 2. - P. 161-166.