DILMAN MD, VLADIMIR

The Neuroendocrine Theory of Aging is attributed to the late Professor Vladimir Dilman of the Petrov Institute of Oncology in St. Petersburg, Russia. It was first proposed by Dilman in English in 1983 and was revised and updated in 1992 by Dilman and Dr. Ward Dean. This theory proposes that aging is due to the loss of receptor sensitivity to feedback inhibition with time, resulting in a progressive shifting of homeostasis and alterations of hormone levels and their effects with time.