INGREDIENTS:
Each tablet contains: Tianeptine (sodium salt) 12.5 mg
Excipients:
Mannitol, corn starch, magnesium stearate, ethyl cellulose, glycerol oleate, polyvidone, sodium carboxymethyl cellulose, silica, talc, titanium dioxide, bicarbonate of soda, wax, sucrose, polysorbate.
PHARMACEUTICAL CLASSIFICATION:
Anti-depressant
THERAPEUTICAL INDICATIONS:

• Neurotic or reactive states of depression
  
• Angiodepressive states with somatic complaints such as digestive problems
  
• Angiodepressive states observed in the alcoholic undergoing detoxification
  

CONTRAINDICATIONS:
This medicine should not be used: With MAO inhibitors (as a rule, there should be an interval of 15 days between a MAOI and Tianeptine treatments) By expectant or nursing mothers. By children of less than 15 years of age. Should you have any doubt, consult your doctor.
ADVERSE EFFECTS:
As with any active pharmaceutical product, this medicine may cause somewhat unpleasant side effects in certain patients. Although such effects are rare, usually mild and temporary, they include: Gastralgia, abdominal pain, dryness of the mouth, anorexia, nausea, vomiting, flatulence, Insomnia, drowsiness, nightmares, asthenia, Tachycardia, extrasystole, precordialgia, Dizziness, headaches, faintness, trembling, upsets, Respiratory discomfort, tightness of the throat, Myalgia, lumbago, Any of the abovementioned should be reported to your doctor or chemist in addition to any adverse effects not mentioned in this leaflet.
INTERACTIONS:
Do not use this product with MAO indicators (see Contraindications)
To prevent accidental interactions between different medicines, inform your doctor or chemist regularly if you should be taking any other pharmaceutical product.
PRECAUTION:

• Any patient about to undergo general anaesthetic should inform the anaesthetist and stop treatment 24 to 48 hours before the medical intervention. Should an emergency operation prove to be necessary, this may be carried out without stopping treatment previously but with the correct operative supervision.
  
• As with other anti-depressants, when treatment is to be stopped, reduce the dosage gradually over a period of 7 to 14 days.
  
• Inform your doctor if you are pregnant or breast-feeding your baby.
  

USE DURING PREGNANCY AND BREAST-FEEDING:
This medicine should not be used during pregnancy or breast-feeding.
EFFECTS ON THE PATIENT'S CAPACITY TO DRIVE OR USE MACHINERY:
Certain patients may experience drowsiness.
Keep in mind the risks involved with the drowsiness that this medicine may cause.
DOSAGE AND DIRECTIONS FOR USE:

• The recommended dosage is 1 tablet taken by mouth, 3 times daily, before breakfast, lunch and dinner.
  
• This dosage should be lowered for patients over 70 years of age and those with renal problems.
  

Do not interrupt treatment without first consulting your doctor and follow his instructions.
OVERDOSE:
In the event of massive swallowing of these tablets, go to your doctor or the nearest hospital.
In any case, stop treatment. Emergency treatment involves the following:

• gastric lavage
  
• cardio-respiratory, metabolic and renal supervision and symptomatic treatment of accompanying alterations and disorders.
  

STORAGE:
Keep this medicine safely out the reach of children. Do not use this medicine once the expiry date printed on the box has passed.