Anacervix –Stimulate and Improve your Powers of Concentration

You know the feeling – can’t quite recall the name of someone you met recently, can’t remember where you last put the car keys or you struggle a little bit more than you used to concentrate and learn something new. Most of us dismiss these little things as simply a sign that we’re getting older but it needn’t be like that. The synergistic action of the components of Anacervix has been specifically formulated to help provide you with the necessary boost you need to help stimulate brain activity and aid concentration.

So how does Anacervix work?

Anacervix works by effectively waking up the brain and helping you to focus on thinking and concentration. It does this through its unique combination of ingredients. Each capsule contains the active ingredients Vincamine and Piracetam (in the proportions 20mg Vincamine and 400mg Piracetam). We look at these key ingredients in more detail below but in essence Vincamine works on improving the circulation of blood whilst Piracetam acts upon cerebral metabolic activation. The net result of this amazing blend of active ingredients is a product that not only stimulates brain activity but also makes you more focused, thereby aiding your powers of concentration.

Let’s look at the two key active ingredients Vincamine and Piracetam in more detail.

Vincamine

Vincamine is a naturally occurring substance that is extracted from the leaves of the Vinca minor plant (commonly known as the periwinkle plant). It is an indole alkaloid (specifically a tryptamine) and is often used as a nootropic agent. Nootropics, sometimes referred to as smart drugs, cognitive enhancers or memory enhancers, are drugs, supplements, functional foods and nutraceuticals that act to improve such things as memory, cognition, motivation, intelligence, concentration and attention. The use of Vincamine is not new - it has been the subject of numerous research papers and has been used therapeutically for over twenty five years.

Vincamine is what is known as a peripheral vasodilator. Vasodilation refers to the widening of the blood vessels that occurs as a result of the relaxation of the smooth muscle cells in the walls of blood vessels. The result of vasodilation is an increase in blood flow - with wider blood vessels, blood can flow more easily. In the case of Vincamine, the vasodilation effects are selective affecting the area within the cranial cavity (the encephalic area). This means that as a result of the vasodilation caused by Vincamine, blood flow to the brain is increased which in turn improves circulation and nutrition to the brain.

Vincamine and some of its derivatives such as Vinpocetine also have a specific activating effect on a part of the brain stem known as the "locus coeruleus" (sometimes spelt locus caeruleus). In unstained brain tissue, the locus coeruleus has a somewhat azure appearance - indeed its name is derived from the Latin words "caeruleus" and "locus" which literally means the “blue spot”.

The locus coeruleus is a nucleus in the brain stem involved with physiological responses to panic and stress. It acts as the principal site for synthesis of norepinepherine in the brain, and is composed of mostly medium-size neurons. These neurons extend throughout the cerebral cortex which is the part of the brain responsible for thinking and planning.

However, as we age the number of locus coeruleus neurons declines with the rate of decline usually being a little faster in men than in women. Not surprisingly, this gradual age related decline in the number of locus coeruleus neurons, coupled with a lessening in the activity of those locus coeruleus neurons that remain, plays a significant role in the reduction of our powers of concentration, alertness, and information processing speed and ability that occurs with aging. But by taking Vincamine, the power of our remaining locus coeruleus neurons is activated, and this can help to offset the age-related decline in activity within the locus coeruleus with the result that our powers of concentration, alertness and information processing can be restored.

The effect of Vincamine on the brain has also been demonstrated by research that examined human brain function as measured by electroencephalogram (EEG). As we age there is a slowing of EEG waves but the use of Vincamine was shown to induce the opposite effect in human brain function with the result that vigilance is improved¹. In this context, vigilance refers to the total state of dynamic neural acitivity.

Given that Vincamine is capable of waking up the brain, its use in the treatment of dementia has also been explored with very encouraging results. For example, in 1996 researchers at the University of Graz in Austria specifically investigated the therapeutic efficacy of Vincamine in the treatment of both primary degenerative and vascular dementia. Primary dementias are characterized by damage to or wasting away of the brain tissue itself and include such conditions as Alzheimer's disease, frontal lobe dementia, and Pick's disease. Vascular dementia (sometimes called multi-infarct dementia) is caused by blood clots in the small blood vessels of the brain. When the clots cut off the blood supply to the brain tissue, the brain cells are damaged and may die. (An infarct is an area of dead tissue caused by obstruction of the circulation).

A total of 142 male and female patients aged between 50 and 85 years from two psychogeriatric centers and two nursing homes completed the Austrian study. In a 12-week double-blind treatment regime study participants were either given 30 mg of Vincamine or a placebo twice daily. As a result of the trial the researchers concluded that Vincamine demonstrated a clearly superior therapeutic effect in patients with mild to moderate primary degenerative or vascular dementia over those receiving the placebo.

With its ability to “wake up” the brain is so many ways, Vincamine truly is a powerful cognition enhancing agent.

Piracetam

Like Vincamine, Piracetam is also classed as a nootropic. Specifically Piracetam belongs to a class of nootropic drugs known as racetams. Piracetam’s affects on the brain are far ranging and include the enhancement of cognition and memory, the slowing of brain aging and the increase of blood flow and oxygen to the brain.

Although Piracetam has been the subject of extensive research, the actual mechanisms by which it works are not yet fully understood. It is thought that it may act on the ion channels that regulate the flow of ions across the membrane in all cells or on the ion carriers themselves (ion carriers are the lipid-soluble molecules that are used to transport ions across the lipid bilayer of cell membranes). Ions such as sodium, potassium and calcium are all essential to life and play a crucial role in the cells of living organisms, particularly in cell membranes. By acting on ion channels or ion carriers, it is thought that Piracetam increases neuron excitability.

Piracetam appears to increase communication between the two hemispheres of the brain by increasing the activity of the corpus callosum (the structure in the brain that facilitates such communication). Piracetam has also has been found to increase blood flow and oxygen consumption in parts of the brain although it’s not clear whether this a primary action of the drug itself or a side effect of the increased brain activity that Piracetam causes. Piracetam is also known to be a specific activator of the metabolism of the brain’s cerebral cortex.

Piracetam is also known to improve the function of the neurotransmitter acetylcholine. Acetycholine is implicated in memory processes. It may also have an effect on NMDA glutamate receptors which again are involved with memory and with learning.

Whatever the action of Piracetam it is clear that it serves to activate the brain by influencing vascular and neuronal functions as well as influencing cognitive function without acting as a sedative or a stimulant. As a result, Piracetam is used throughout Europe, Asia, South America and the US to treat a wide range of diseases and conditions. These include:

Aiding stroke recovery
Improving cognitive function in Alzheimer’s Disease sufferers, dementia sufferers and schizophrenics
Ameliorating the effects of dyslexia
Ameliorating the effects of Down’s Syndrome
Treating cognitive impairment brought about by alcoholism
Treating patients with cranio-cerebral trauma (essentially accidents to the head) as a way of stimulating brain activity

Piracetam may even be useful as part of the therapy regime for certain blood disorders as a long-term treatment for clotting, coagulation, and vasospastic disorders such as Raynaud’s phenomenon and deep-vein thrombosis.

But it isn’t just those who are ill that may benefit from Piracetam and its ability to activate the brain. Piracetam improves cognitive performance in healthy people as well. For example in one study 16 students from University College, Cardiff, Wales, took part in a double blind trial. After 14 days of 400mg of Piracetam daily, the study clearly demonstrated that Piracetam significantly increased their verbal learning skills and memory³. Indeed, such is the benefit that nootropics like Piracetam can bestow on people’s learning abilities that their use is becoming more widespread amongst student populations.

Piracetam may also have a direct role in the fight against aging. Researchers have been able to demonstrate that Piracetam can reverse the effects of aging in the brains of mice and appears to be able to reduce levels of lipofuscin in the brains of rats^4,5,6. The accumulation of lipofuscin is a common sign of aging. Indeed, it is considered to be one of the aging or "wear and tear" pigments, and is found in the liver, adrenals, heart muscle, kidneys, nerve cells and ganglion cells.

What else is Anacervix used for?

With the powerful combination of Vincamine and Piracetam, not only does Anacervix wake up the brain and aid your ability to concentrate, but, by employing the effects discussed above, it also offers treatment for:

Progressive and chronic neuronal/cerebral insufficiencies
Degeneration of thinking associated with age or intoxication
Cranial trauma
Cerebral insufficiencies as a result of acute vascular accidents
Organic and psychological disorders from cerebral hypoxia
Learning difficulties and behavioural alterations

It’s easy to see then that with two such powerful nootropic agents at work, the unique synergistic blend found in Anacervix stimulates and activates the brain, giving you that all important boost to your cognitive function, focus your thinking, memory and learning capabilities and aid your concentration.

Dosage

Take three to six capsules per day. It is suggested that Anacervix should be taken at 9am, 1pm and 5pm, though the last dose may be taken later if evening activity is planned. It is preferable to take Anacervix after main meals.

Side effects

Anacervix has proven to be perfectly tolerated

Warnings

Care should be taken with cases of cerebral hypertension. As with any cerebral activator, it is not recommended to take the medication in the evening, as it may then cause some problems falling asleep.

Do not take Anacrevix if you are pregnant.

Anacervix may stimulate the action of barbiturates.

References

B. Saletu & J. Grunberger. Memory dysfunction and vigilance; neurophysiological and psychopharmacological aspects. Ann NY Acad Sci 444, 406-27. 1985
Fischhof Pk, Moslinger-Gehmayr R, Herrmann WM, Friedmann A, Russmann DL. Therapeutic efficacy of Vincamine in dementia. Neuropsychobiology 1996;34(1):29-35.
Dimond, SJ; Brouwers. Increase in the power of human memory in normal man through the use of drugs. Psychopharmacology 49 (3): 307–9. 1976
Pilch; Müller. Piracetam elevates muscarinic cholinergic receptor density in the frontal cortex of aged but not of young mice. Psychopharmacology 94 (1): 74. 1988
Stoll; Schubert; Müller. Age-related deficits of central muscarinic cholinergic receptor function in the mouse: partial restoration by chronic Piracetam treatment. Neurobiology of aging 13 (1): 39–44. 1992
Paula-Barbosa, Brandão; Pinho; Andrade; Madeira; Cadete-Leite The effects of Piracetam on lipofuscin of the rat cerebellar and hippocampal neurons after long-term alcohol treatment and withdrawal: a quantitative study. Alcoholism, clinical and experimental research 15 (5): 834–8. 1991

Activate your brain with Anacervix!

Anacervix improves blood circulation and cerebral metabolic activity, stimulating the brain and aiding concentration

Anacervix, through the synergistic action of its components is a complete treatment for cerebral vasculatory processes. It combines the blood circulation improving action of Vincamine (the alkaloid extract of vinca minor, similar to Vinpocetine) with the cerebral metabolic activation of Piracetam to boost brain activity and focus thinking.

Anacervix is used for the treatment of progressive and chronic neuronal insufficiencies as well as learning difficulties, as well as the degeneration of thinking associated with age or intoxication. Based on the results of a trial conducted in 1996, the therapeutic effect of Vincamine was superior to a placebo in patients with mild to moderate dementia of degenerative and vascular etiologies.

In addition, Anacervix is sometimes used in the treatment of cranial trauma, (accidents to the head) to help stimulate brain activity.

Dosage:
Take three to six capsules (each capsule contains 400mg of Piracetam and 20mg of Vincamine) per day. 9am, 1pm and 5pm are the suggested times to take Anacervix, though the last dose may be taken later if evening activity is planned.

Caution:
Care should be taken with cases of cerebral hypertension. As with any cerebral activator, it is not recommended to take the medication in the evening, as it may then cause some problems falling asleep.

What our customers say...

I like this product, it is a clever combination of two of my favorite smart drugs.
P.W.H., Minnesota.

Full Ingredients and Approved Uses: Anacervix